Bone‐targeted exosomes: strategies and applications

J Wang, X Li, S Wang, J Cui, X Ren… - Advanced healthcare …, 2023 - Wiley Online Library
As the global population ages, bone‐related diseases have increasingly become a major
social problem threatening human health. Exosomes, as natural cell products, have been …

Cerium oxide nanoparticle modified scaffold interface enhances vascularization of bone grafts by activating calcium channel of mesenchymal stem cells

J Xiang, J Li, J He, X Tang, C Dou, Z Cao… - … applied materials & …, 2016 - ACS Publications
Insufficient blood perfusion is one of the critical problems that hamper the clinical application
of tissue engineering bone (TEB). Current methods for improving blood vessel distribution in …

[Retracted] MSN@ IL‐4 Sustainingly Mediates Macrophagocyte M2 Polarization and Relieves Osteoblast Damage via NF‐κB Pathway‐Associated Apoptosis

C Shi, F Yuan, Z Li, Z Zheng, C Yuan… - BioMed Research …, 2022 - Wiley Online Library
Background. The microenvironment of bone defects displayed that M2 polarization of
macrophagocyte could promote the osteoblast growth and benefit the wound healing. Bone …

[HTML][HTML] Antibiotic-loaded phosphatidylcholine inhibits staphylococcal bone infection

JA Jennings, KE Beenken, RA Skinner… - World Journal of …, 2016 - ncbi.nlm.nih.gov
AIM To test antibiotic-loaded coating for efficacy in reducing bacterial biofilm and
development of osteomyelitis in an orthopaedic model of implant infection. METHODS …

[HTML][HTML] Co-culture bioprinting of tissue-engineered bone-periosteum biphasic complex for repairing critical-sized skull defects in rabbits

D Zhao, Y Wang, Z Yu, C Wang, H Zhang… - … Journal of Bioprinting, 2023 - ncbi.nlm.nih.gov
Tissue engineering based on bioprinting technology has broad prospects in the treatment of
critical-sized bone defect. Nevertheless, it is challenging to construct composite tissues or …

Multipotent adult progenitor cells on an allograft scaffold facilitate the bone repair process

A LoGuidice, A Houlihan… - Journal of tissue …, 2016 - journals.sagepub.com
Multipotent adult progenitor cells are a recently described population of stem cells derived
from the bone marrow stroma. Research has demonstrated the potential of multipotent adult …

[HTML][HTML] Dendronized chitosan hydrogel with GIT1 to accelerate bone defect repair through increasing local neovascular amount

L Cheng, Z Zhou, Q Li, W Li, X Li, G Li, J Fan, L Yu… - Bone Reports, 2023 - Elsevier
Bone defects have long been a major healthcare issue because of the difficulties in
regenerating bone mass volume and the high cost of treatment. G protein-coupled receptor …

Effects of cryopreservation on excretory function, cellular adhesion molecules and vessel lumen formation in human umbilical vein endothelial cells

G Cai, B Lai, H Hong, P Lin… - Molecular …, 2017 - spandidos-publications.com
Cryopreservation is widely used in regenerative medicine for tissue preservation. In the
present study, the effects of cryopreservation on excretory function, cellular adhesion …

Craniofacial regenerative medicine

BT Smith, E Watson, IA Hanna, JC Melville… - Principles of …, 2019 - Elsevier
The complex architecture of craniofacial anatomy, different mechanical demands, and
variable local environments make the application of uniform tissue engineering strategies …

Vascular Supply and Bone Marrow Concentrate for the Improvement of Allograft in Bone Defects: A Comparative In Vivo Study

M Cavallo, M Maglio, A Parrilli, S Pagani… - Journal of Surgical …, 2020 - Elsevier
Background Surgical repair of critical-sized bone defects still remains a big challenge in
orthopedic surgery. Biological enhancement, such as growth factors or cells, can stimulate a …