Global control of hepatitis C: where challenge meets opportunity

DL Thomas - Nature medicine, 2013 - nature.com
We are entering an important new chapter in the story of hepatitis C virus (HCV) infection.
There are clear challenges and opportunities. On the one hand, new HCV infections are still …

[HTML][HTML] Age and cancer risk: a potentially modifiable relationship

MC White, DM Holman, JE Boehm, LA Peipins… - American journal of …, 2014 - Elsevier
This article challenges the idea that cancer cannot be prevented among older adults by
examining different aspects of the relationship between age and cancer. Although the …

Screening for hepatitis C virus infection in adolescents and adults: updated evidence report and systematic review for the US Preventive Services Task Force

R Chou, T Dana, R Fu, B Zakher, J Wagner, S Ramirez… - JAMA, 2020 - jamanetwork.com
Importance A 2013 review for the US Preventive Services Task Force (USPSTF) of hepatitis
C virus (HCV) screening found interferon-based antiviral therapy associated with increased …

[PDF][PDF] 17‐beta hydroxysteroid dehydrogenase 13 is a hepatic retinol dehydrogenase associated with histological features of nonalcoholic fatty liver disease

Y Ma, OV Belyaeva, PM Brown, K Fujita, K Valles… - …, 2019 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease. A
single‐nucleotide polymorphism (SNP), rs6834314, was associated with serum liver …

The cost-effectiveness, health benefits, and financial costs of new antiviral treatments for hepatitis C virus

DB Rein, JS Wittenborn, BD Smith… - Clinical infectious …, 2015 - academic.oup.com
Background. New hepatitis C virus (HCV) treatments deliver higher cure rates with fewer
contraindications, increasing demand for treatment and healthcare costs. The cost …

Strategies for hepatitis C testing and linkage to care for vulnerable populations: point-of-care and standard HCV testing in a mobile medical clinic

JP Morano, A Zelenev, A Lombard, R Marcus… - Journal of community …, 2014 - Springer
Despite new Hepatitis C virus (HCV) therapeutic advances, challenges remain for HCV
testing and linking patients to care. A point-of-care (POC) HCV antibody testing strategy was …

Evaluation of Fontan liver disease: correlation of transjugular liver biopsy with magnetic resonance and hemodynamics

JA Silva‐Sepulveda, Y Fonseca, I Vodkin… - Congenital heart …, 2019 - Wiley Online Library
Introduction Liver fibrosis and cirrhosis are late complications in Fontan palliation. Liver
biopsy is the gold standard. The goal of this study is to correlate transjugular liver biopsy …

The impact of direct‐acting anti‐virals on the hepatitis C care cascade: identifying progress and gaps towards hepatitis C elimination in the United States

J Chhatwal, Q Chen, ED Bethea, C Hur… - Alimentary …, 2019 - Wiley Online Library
Background The hepatitis C virus (HCV) care cascade has changed dramatically following
the introduction of direct‐acting anti‐virals (DAAs). Up‐to‐date estimates of the cascade are …

Increasing prevalence of cirrhosis among US adults aware or unaware of their chronic hepatitis C virus infection

P Udompap, A Mannalithara, NY Heo, D Kim… - Journal of …, 2016 - Elsevier
Background & Aims Cirrhosis from hepatitis C virus (HCV) infection is a major cause of end-
stage liver disease and hepatocellular carcinoma worldwide. We determine the prevalence …

Diagnosis and management of hepatitis C

T Wilkins, M Akhtar, E Gititu, C Jalluri… - American family physician, 2015 - aafp.org
Hepatitis C virus (HCV) infection, a major cause of chronic liver disease and cirrhosis, is
predominantly transmitted by exposure to blood or body fluids. The infection progresses to a …