Liver sinusoidal endothelial cells: Physiology and role in liver diseases

J Poisson, S Lemoinne, C Boulanger, F Durand… - Journal of …, 2017 - Elsevier
Liver sinusoidal endothelial cells (LSECs) are highly specialized endothelial cells
representing the interface between blood cells on the one side and hepatocytes and hepatic …

The tumor radiobiology of SRS and SBRT: are more than the 5 Rs involved?

JM Brown, DJ Carlson, DJ Brenner - International Journal of Radiation …, 2014 - Elsevier
Stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT), also known
as stereotactic ablative radiation therapy (SABR), are rapidly becoming accepted practice for …

Caspase-11–mediated endothelial pyroptosis underlies endotoxemia-induced lung injury

KT Cheng, S Xiong, Z Ye, Z Hong, A Di… - The Journal of …, 2017 - Am Soc Clin Investig
Acute lung injury is a leading cause of death in bacterial sepsis due to the wholesale
destruction of the lung endothelial barrier, which results in protein-rich lung edema, influx of …

Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability

SM Evrard, L Lecce, KC Michelis… - Nature …, 2016 - nature.com
Endothelial to mesenchymal transition (EndMT) plays a major role during development, and
also contributes to several adult cardiovascular diseases. Importantly, mesenchymal cells …

Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis

DJ Hicklin, LM Ellis - Journal of clinical oncology, 2005 - ascopubs.org
New blood vessel formation (angiogenesis) is a fundamental event in the process of tumor
growth and metastatic dissemination. Hence, the molecular basis of tumor angiogenesis has …

Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice

M Kioi, H Vogel, G Schultz, RM Hoffman… - The Journal of …, 2010 - Am Soc Clin Investig
Despite the high doses of radiation delivered in the treatment of patients with glioblastoma
multiforme (GBM), the tumors invariably recur within the irradiation field, resulting in a low …

TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling

BC Cooley, J Nevado, J Mellad, D Yang… - Science translational …, 2014 - science.org
Veins grafted into an arterial environment undergo a complex vascular remodeling process.
Pathologic vascular remodeling often results in stenosed or occluded conduit grafts …

[PDF][PDF] Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors

M De Palma, MA Venneri, R Galli, LS Sergi, LS Politi… - Cancer cell, 2005 - cell.com
Bone marrow-derived cells contribute to tumor angiogenesis. Here, we demonstrate that
monocytes expressing the Tie2 receptor (Tie2-expressing monocytes [TEMs])(1) are a …

Origins of the tumor microenvironment: Quantitative assessment of adipose-derived and bone marrow–derived stroma

S Kidd, E Spaeth, K Watson, J Burks, H Lu, A Klopp… - PloS one, 2012 - journals.plos.org
To meet the requirements for rapid tumor growth, a complex array of non-neoplastic cells are
recruited to the tumor microenvironment. These cells facilitate tumor development by …

Tumour vascularization: sprouting angiogenesis and beyond

F Hillen, AW Griffioen - Cancer and Metastasis Reviews, 2007 - Springer
Tumour angiogenesis is a fast growing domain in tumour biology. Many growth factors and
mechanisms have been unravelled. For almost 30 years, the sprouting of new vessels out of …