In humans, the combination of all sex-specific genetic, epigenetic, and hormonal influences
of biologic sex produces different in vivo environments for male and female cells. We dissect …

ABSTRACT Introduction: Anorexia nervosa (AN), bulimia nervosa (BN) and binge eating
disorder (BED) are the primary eating disorders (EDs). The only psychopharmacological …

A previous study demonstrated that a high-fat diet (HFD), administered for one-three-days,
induces hypothalamic inflammation before obesity's established, and the long term affects …

All forms of diabetes mellitus are characterized by chronic hyperglycemia, resulting in the
development of a number of microvascular and macrovascular pathologies. Diabetes is also …

Background Average daily gain (ADG) and lean meat percentage (LMP) are the main
production performance indicators of pigs. Nevertheless, the genetic architecture of ADG …

Antipsychotic-induced weight gain (AIWG) is a common side effect of antipsychotic
medication and may contribute to diabetes and coronary heart disease. To expand the …

The hypothalamus plays a crucial role in body weight homeostasis through an intricate
network of neuronal circuits that are under the precise regulation of peripheral hormones …

Introduction The timing of maternal exposure to air pollution is crucial to define metabolic
changes in the offspring. Here we aimed to determine the most critical period of maternal …

Objective Open trials suggest phentermine/topiramate ER (PHEN/TPM‐ER), food and drug
administration (FDA) approved for obesity, has utility for binge eating. With no randomized …

There is an urgent need for effective pharmacological therapies to help tackle the growing
obesity epidemic and the healthcare crisis it poses. The past 3 years have seen approval of …