[HTML][HTML] The role of tissue transglutaminase in cancer cell initiation, survival and progression
C Tabolacci, A De Martino, C Mischiati, G Feriotto… - Medical …, 2019 - mdpi.com
Tissue transglutaminase (transglutaminase type 2; TG2) is the most ubiquitously expressed
member of the transglutaminase family (EC 2.3. 2.13) that catalyzes specific post …
member of the transglutaminase family (EC 2.3. 2.13) that catalyzes specific post …
Protein transamidation by transglutaminase 2 in cells: a disputed Ca2+‐dependent action of a multifunctional protein
Transglutaminase 2 (TG2) is the first described cellular member of an enzyme family
catalyzing Ca2+‐dependent transamidation of proteins. During the last two decades its …
catalyzing Ca2+‐dependent transamidation of proteins. During the last two decades its …
Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis
T Liu, AEL Tee, A Porro, SA Smith… - Proceedings of the …, 2007 - National Acad Sciences
Histone deacetylase (HDAC) inhibitors reactivate tumor suppressor gene transcription;
induce cancer cell differentiation, growth arrest, and programmed cell death; and are among …
induce cancer cell differentiation, growth arrest, and programmed cell death; and are among …
Role of transglutaminase 2 in celiac disease pathogenesis
C Klöck, TR DiRaimondo, C Khosla - Seminars in immunopathology, 2012 - Springer
A number of lines of evidence suggest that transglutaminase 2 (TG2) may be one of the
earliest disease-relevant proteins to encounter immunotoxic gluten in the celiac gut. These …
earliest disease-relevant proteins to encounter immunotoxic gluten in the celiac gut. These …
The transglutaminase 2 gene ( TGM2 ), a potential molecular marker for chemotherapeutic drug sensitivity, is epigenetically silenced in breast cancer
L Ai, WJ Kim, B Demircan, LM Dyer, KJ Bray… - …, 2008 - academic.oup.com
Tissue transglutaminase (TG2) is a ubiquitously expressed enzyme capable of catalyzing
protein cross-links. TG2-dependent cross-links are important in extracellular matrix integrity …
protein cross-links. TG2-dependent cross-links are important in extracellular matrix integrity …
[HTML][HTML] Phosphorylation of histones by tissue transglutaminase
Tissue transglutaminase 2 (TG2) has recently been shown to have intrinsic serine/threonine
kinase activity. Since histones are known to be cross-linked by TG2, we investigated …
kinase activity. Since histones are known to be cross-linked by TG2, we investigated …
[HTML][HTML] Redefining the BH3 death domain as a 'short linear motif'
B cell lymphoma-2 (BCL-2)-related proteins control programmed cell death through a
complex network of protein–protein interactions mediated by BCL-2 homology 3 (BH3) …
complex network of protein–protein interactions mediated by BCL-2 homology 3 (BH3) …
Retinoic acid receptors and tissue-transglutaminase mediate short-term effect of retinoic acid on migration and invasion of neuroblastoma SH-SY5Y cells
Long-term treatment with all trans-retinoic acid (RA) induces neuronal differentiation and
apoptosis. However, the effect of short-term RA treatment on cell proliferation, migration and …
apoptosis. However, the effect of short-term RA treatment on cell proliferation, migration and …
Functional significance of five noncanonical Ca2+‐binding sites of human transglutaminase 2 characterized by site‐directed mutagenesis
The multifunctional tissue transglutaminase 2 (TG2) has a four‐domain structure with
several Ca2+‐regulated biochemical activities, including transglutamylation and GTP …
several Ca2+‐regulated biochemical activities, including transglutamylation and GTP …
[HTML][HTML] The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma
Glioblastoma is the most common malignant primary brain tumor. To date, clinically relevant
biomarkers are restricted to isocitrate dehydrogenase (IDH) gene 1 or 2 mutations and O6 …
biomarkers are restricted to isocitrate dehydrogenase (IDH) gene 1 or 2 mutations and O6 …