Hong Kong has been recently attacked by the coronavirus disease-2019 (COVID-19). In late
January 2020, it's shown a steadily increasing trend of confirmed cases. There is a 257 in …

METHODS We conducted a systematic study which represents one of the most
comprehensive effort to quantify global HCV epidemiology, using the best available …

Conclusions Our findings indicate that LINC00665 is involved in the NF‐κB signaling
activation in HCC cells and that the inflammatory LINC00665/PKR/NF‐κB loop plays …

Background Chronic hepatitis C virus (HCV) infection is more prevalent among patients who
have chronic kidney disease than among those who do not have the disease. Patients with …

Hepatitis C virus (HCV) exhibits high genetic diversity, characterized by regional variations
in genotype prevalence. This poses a challenge to the improved development of vaccines …

Macrophages represent a major cell type of innate immunity and have emerged as a critical
player and therapeutic target in many chronic inflammatory diseases. Hepatic macrophages …

Exhausted T cells express multiple co-inhibitory molecules that impair their function and limit
immunity to chronic viral infection. Defining novel markers of exhaustion is important both for …

The aspartate aminotransferase‐to‐platelet ratio index (APRI), a tool with limited expense
and widespread availability, is a promising noninvasive alternative to liver biopsy for …

At present chronic liver disease (CLD), the third commonest cause of premature death in the
United Kingdom is detected late, when interventions are ineffective, resulting in …

Hepatitis C virus (HCV) infection is the most common blood-borne infection in the United
States, with estimates of 4 million HCV-infected individuals in the United States and 170 …