Neurocognitive disorders—including delirium, mild cognitive impairment and dementia—are
characterized by decline from a previously attained level of cognitive functioning. These …

To develop effective disease-modifying therapies for neurodegenerative diseases, reliable
markers of diagnosis, disease activity and progression are a research priority. The fact that …

In the past 30 years there has been a growing body of research using different methods
(behavioural, electrophysiological, neuropsychological, TMS and imaging studies) asking …

The neural pathways and brain regions involved in eye movements during ocular fixation
and gaze control include the cerebrum, brainstem and cerebellum, and abnormal eye …

Frontotemporal lobar degeneration (FTLD) is the umbrella term encompassing a
heterogeneous group of pathological disorders. With recent discoveries, the FTLDs have …

A major recent discovery was the identification of an expansion of a non-coding GGGGCC
hexanucleotide repeat in the C9ORF72 gene in patients with frontotemporal dementia and …

Frontotemporal dementia (FTD) encompasses a spectrum of clinical syndromes
characterized by progressive executive, behavioural and language dysfunction. The various …

The first reports of disorders that in terms of cognitive and behavioral symptoms resemble
frontotemporal dementia (FTD) and in terms of motor symptoms resemble amyotrophic …

The behavioural variant of frontotemporal dementia is a progressive neurodegenerative
syndrome characterized by changes in personality and behaviour. It is typically associated …

Rare mutations in the gene encoding for tau (MAPT, microtubule-associated protein tau)
cause frontotemporal dementia-spectrum (FTD-s) disorders, including FTD, progressive …