Characterizing metabolism in cancer is crucial for understanding tumor biology and for
developing potential therapies. Although most metabolic investigations analyze averaged …

Vibrational spectroscopy techniques have demonstrated potential to provide non-
destructive, rapid, clinically relevant diagnostic information. Early detection is the most …

Cells must duplicate their mass in order to proliferate. Glucose and glutamine are the major
nutrients consumed by proliferating mammalian cells, but the extent to which these and …

Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …

The gold standard in histopathology relies on manual investigation of stained tissue
biopsies. A sensitive and quantitative method for in situ tissue specimen inspection is highly …

Raman spectra of cells and nuclei from cultures in the plateau (nonproliferating) and
exponential (proliferating) phases of growth were measured and show that Raman …

Failure to precisely distinguish malignant from healthy tissue has severe implications for
breast cancer surgical outcomes. Clinical prognoses depend on precisely distinguishing …

The most common initial treatment received by patients with a brain tumour is surgical
removal of the growth. Precise histopathological diagnosis of brain tumours is to some …

Excellent multiplexing capability, molecular specificity, high sensitivity and the potential of
resolving complex molecular level biological compositions augmented the diagnostic …

Raman spectroscopy is a molecular vibrational spectroscopic technique that is capable of
optically probing the biomolecular changes associated with diseased transformation. The …