The individual response to ionizing radiation (IR) raises a number of medical, scientific, and
societal issues. While the term “radiosensitivity” was used by the pioneers at the beginning …

Ataxia-telangiectasia or AT is a fatal progressive neurological disease of children. The
symptoms indicate disruptions in the development of such diverse body parts as cerebellum …

Abstract Background Coronavirus disease 2019 (COVID-19) exhibits a wide spectrum of
clinical manifestations, ranging from asymptomatic to critical conditions. Understanding the …

PURPOSE Fanconi anemia (FA) and ataxia-telangiectasia (AT) are rare inherited
syndromes characterized by abnormal DNA damage response and caused by pathogenic …

Ataxia-telangiectasia (AT) is a rare autosomal recessive neurodegenerative multisystem
disorder. A minority of AT patients can present late-onset atypical presentations due to …

Microrchidia CW-type zinc finger 2 (MORC2) gene encodes a protein expressed in all
tissues and enriched in the brain. MORC2 protein is composed of a catalytic ATPase …

Dendritic cells (DCs) are crucial cells for initiating and maintaining immune response. They
play critical role in homeostasis, inflammation, and autoimmunity. A number of molecules …

Autosomal recessive cerebellar ataxias (ARCAs) are a heterogeneous group of rare
neurodegenerative inherited disorders. The resulting motor incoordination and progressive …

Protein kinases act as a trigger for regulating a wide range of cellular processes including
development, survival, apoptosis, control of metabolism, transcription signals, and beyond …

Objective To review the pathobiology, irradiation dosimetric parameters and other risk
factors, and therapy of radiation-induced gastric damage (RIGD). Background RIGD is a side …