Mechanisms of nanoparticle transport across intestinal tissue: an oral delivery perspective
Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …
Enhanced oral bioavailability from food protein nanoparticles: A mini review
The oral route is the most desirable drug administration path. The oral bioavailability is
always compromised from the poor physicochemical and/or biopharmaceutical properties of …
always compromised from the poor physicochemical and/or biopharmaceutical properties of …
Preparation of mucoadhesive methacrylated chitosan nanoparticles for delivery of ciprofloxacin
Mucoadhesive polymers and their nanoparticles have attracted a lot of attention in
pharmaceutical applications, especially transmucosal drug delivery (TDD). Mucoadhesive …
pharmaceutical applications, especially transmucosal drug delivery (TDD). Mucoadhesive …
Challenges and opportunities in the development of mucosal mRNA vaccines
mRNA vaccines have played a critical role in controlling the SARS-CoV-2 pandemic, and
are being actively studied for use in other diseases. There is a growing interest in applying …
are being actively studied for use in other diseases. There is a growing interest in applying …
Oral nanomedicine biointeractions in the gastrointestinal tract in health and disease
Oral administration is the preferred route of administration based on the convenience for and
compliance of the patient. Oral nanomedicines have been developed to overcome the …
compliance of the patient. Oral nanomedicines have been developed to overcome the …
Advances in chitosan-based drug delivery systems: A comprehensive review for therapeutic applications
Chitosan (CS), a biocompatible and biodegradable polymer produced from chitin, has
attracted interest in drug delivery due to its unique properties and diverse applications. Over …
attracted interest in drug delivery due to its unique properties and diverse applications. Over …
Native gastrointestinal mucus: critical features and techniques for studying interactions with drugs, drug carriers, and bacteria
CM Wang, MT Fernez, BM Woolston… - Advanced drug delivery …, 2023 - Elsevier
Gastrointestinal mucus plays essential roles in modulating interactions between intestinal
lumen contents, including orally delivered drug carriers and the gut microbiome, and …
lumen contents, including orally delivered drug carriers and the gut microbiome, and …
β-Glucan and fatty acid based mucoadhesive carrier for gastrointestinal tract specific local and sustained drug delivery
The oral route is considered the most convenient route of drug administration for both
systemic and local delivery. Besides stability and transportation, another unmet but …
systemic and local delivery. Besides stability and transportation, another unmet but …
Classification and design strategies of polysaccharide-based nano-nutrient delivery systems for enhanced bioactivity and targeted delivery: A review
Z Wang, S Fu, Y Guo, Y Han, C Ma, R Li… - International Journal of …, 2023 - Elsevier
Since many nutrients are highly sensitive, they cannot be absorbed and utilized efficiently by
the body. Using nano-delivery systems to encapsulate nutrients is an effective method of …
the body. Using nano-delivery systems to encapsulate nutrients is an effective method of …
Recent advances in mucus-penetrating nanomedicines for oral treatment of colonic diseases
C Xu, H Xu, Z Zhu, X Shi, B Xiao - Expert Opinion on Drug Delivery, 2023 - Taylor & Francis
Introduction Oral administration is the most common route for treating colonic diseases that
present increased incidences in recent years. Colonic mucus is a critical rate-limiting barrier …
present increased incidences in recent years. Colonic mucus is a critical rate-limiting barrier …