Coumarin compounds represent an important type of naturally occurring and synthetic
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …

Coumarins are oxygen-containing molecules with specific benzopyrone nucleus. Different
coumarins are identified as antineurodegeneratives, anticoagulants, antioxidants …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive and
behavioral impairment. Curcumin-loaded mesoporous silica nanoparticles (MSN-CCM) can …

Depression is a major mental disease that is ranked as the fourth leading cause of disability.
In order to avoid unwanted adverse reactions, as well as improve efficacy, current …

Natural and synthetic coumarins have been extensively described in the literature as
effective drugs with several pharmacological activities. Many valuable publications have …

Coumarins are widely distributed, plant-derived, 2 H-1-benzopyran-2-one derivatives which
have attracted intense interest in recent years as a result of their diverse and potent …

The aim of this study was to investigate the antidepressant-like effect of fractions from
Rosmarinus officinalis L.: ethyl acetate 1 and 2 (AcOEt1 and 2), hexane (HEX), ethanolic …

Ursolic acid, a constituent from Rosmarinus officinalis, is a triterpenoid compound which has
been extensively known for its anticancer and antioxidant properties. In the present study …

A series of 3-phenylcoumarins were synthesized and screened for potential antidepressant
activity by tail suspension test (TST) in mice. Three compounds (6, 7 and 13) exhibited …

A number of psychiatric disorders, including anxiety, schizophrenia, Parkinson's disease,
depression and others CNS diseases are known to induce defects in the function of neural …