The cytotoxic anti-cancer drugs cisplatin, paclitaxel, doxorubicin, 5-fluorouracil (5-FU), as
well as targeted drugs including imatinib, erlotinib, and nivolumab, play key roles in clinical …

The tumor necrosis factor-α-induced protein 8-like (TIPE/TNFAIP8) family is a recently
identified family of proteins that is strongly associated with the regulation of immunity and …

Background Cisplatin (DDP) is the first-line chemotherapeutic drug for non-small cell lung
cancer (NSCLC), and long-term DDP stimulation increased resistance of NSCLC cells to this …

Abstract Ethnopharmacological relevance Sophora davidii (Franch.) Skeels Flower (SDF) is
a characteristic folk medicine in Yunnan and Guizhou, which can be used to prevent the …

Background Long non-coding RNA H19 (lncRNA H19) has been implicated in
tumorigenesis and metastasis of breast cancer through regulating epithelial to mesenchymal …

Background: Metastasis is the leading cause of death in colorectal cancer (CRC) patients. It
is regulated mainly by tumor cell angiogenesis, and angiogenesis is caused by the binding …

Background Cisplatin is the first-line chemotherapeutic drug for non-small cell lung cancer
(NSCLC), and emerging evidences suggests that targeting circular RNAs (circRNAs) is an …

Autophagy is conserved cellular machinery that degrades un-usable proteins and cellular
components and has a crucial role in the pathogenesis and drug resistance of various …

Tumor necrosis factor-α-induced protein 8 (TNFAIP8) expression has been linked to tumor
progression in various cancer types, but the detailed mechanisms of TNFAIP8 are not fully …

Non-small cell lung cancer (NSCLC) is one of the most common malignant tumors
worldwide. Clinical success is suboptimal owing to late diagnosis, limited treatment options …