The solid mechanics of cancer and strategies for improved therapy

T Stylianopoulos - Journal of biomechanical …, 2017 - asmedigitalcollection.asme.org
Tumor progression and response to treatment is determined in large part by the generation
of mechanical stresses that stem from both the solid and the fluid phase of the tumor …

An asymptotic homogenization approach to the microstructural evolution of heterogeneous media

A Ramírez-Torres, S Di Stefano, A Grillo… - International Journal of …, 2018 - Elsevier
In the present work, we apply the asymptotic homogenization technique to the equations
describing the dynamics of a heterogeneous material with evolving micro-structure, thereby …

[HTML][HTML] In-Silico Modeling of Tumor Spheroid Formation and Growth

M Amereh, R Edwards, M Akbari, B Nadler - Micromachines, 2021 - mdpi.com
Mathematical modeling has significant potential for understanding of biological models of
cancer and to accelerate the progress in cross-disciplinary approaches of cancer treatment …

Self-influenced growth through evolving material inhomogeneities

S Di Stefano, A Ramírez-Torres, R Penta… - International Journal of …, 2018 - Elsevier
We reformulate a model of avascular tumour growth in which the tumour tissue is studied as
a biphasic medium featuring an interstitial fluid and a solid phase. The description of growth …

[HTML][HTML] In-silico study of asymmetric remodeling of tumors in response to external biochemical stimuli

M Amereh, M Akbari, B Nadler - Scientific Reports, 2023 - nature.com
Among different hallmarks of cancer, understanding biomechanics of tumor growth and
remodeling benefits the most from the theoretical framework of continuum mechanics. Tumor …

Improvement of nonlocal Pennes heat transfer equation in fractal dimensions in the analysis of tumor growth

RA El-Nabulsi, W Anukool - Acta Mechanica, 2023 - Springer
Pennes' bioheat equation is considered one of the most prevalent mathematical equations
used to estimate the temperature profile of a tumor in a human body when subjected to …

The influence of anisotropic growth and geometry on the stress of solid tumors

A Ramírez-Torres, R Rodríguez-Ramos… - International Journal of …, 2017 - Elsevier
Solid stresses can affect tumor patho-physiology in at least two ways: directly, by
compressing cancer and stromal cells, and indirectly, by deforming blood and lymphatic …

[HTML][HTML] Cell – extracellular matrix interaction in glioma growth. In silico model

V Kalinin - Journal of Integrative Bioinformatics, 2020 - degruyter.com
The study aims to investigate the role of viscoelastic interactions between cells and
extracellular matrix (ECM) in avascular tumor growth. Computer simulations of glioma …

Biomechanical modelling of spinal tumour anisotropic growth

I Katsamba, P Evangelidis… - … of the Royal …, 2020 - royalsocietypublishing.org
Biomechanical abnormalities of solid tumours involve stiffening of the tissue and
accumulation of mechanical stresses. Both abnormalities affect cancer cell proliferation and …

[HTML][HTML] Mathematical modeling of spherical shell-type pattern of tumor invasion

M Amereh, H Struchtrup, B Nadler - Symmetry, 2023 - mdpi.com
Cancer cell migration, as the principal element of tumor invasion, involves different cellular
mechanisms. Various modes of cell migration including single and collective motions …