Toxin-mediated streptococcal and staphylococcal disease
SM Manders - Journal of the American Academy of Dermatology, 1998 - Elsevier
After several decades of seemingly decreasing virulence, streptococcal and staphylococcal
infections have reemerged as a major source of morbidity and mortality. Within the past 2 …
infections have reemerged as a major source of morbidity and mortality. Within the past 2 …
Superantigens
B Fleischer - Apmis, 1994 - Wiley Online Library
“Superantigens” is the term for a group of molecules that have in common an extremely
potent stimulatory activity for T lymphocytes of several species. They stimulate CD4+, CD8+ …
potent stimulatory activity for T lymphocytes of several species. They stimulate CD4+, CD8+ …
Association of Erythrodermic Cutaneous T-Cell Lymphoma, Superantigen-Positive Staphylococcus aureus, and Oligoclonal T-Cell Receptor Vβ Gene Expansion
CM Jackow, JC Cather, V Hearne… - Blood, The Journal …, 1997 - ashpublications.org
Forty-two patients with cutaneous T-cell lymphoma, including 31 with exfoliative
erythroderma or Sezary syndrome and 11 with mycosis fungoides, were studied for the …
erythroderma or Sezary syndrome and 11 with mycosis fungoides, were studied for the …
[HTML][HTML] Selection of a broad repertoire of CD4+ T cells in H-2Ma0/0 mice
S Tourne, T Miyazaki, A Oxenius, L Klein, T Fehr… - Immunity, 1997 - cell.com
According to past reports, H-2Ma 0/0 mice express a single major histocompatiblity complex
class II molecule, A b, heavily loaded with a single peptide derived from the invariant chain …
class II molecule, A b, heavily loaded with a single peptide derived from the invariant chain …
Antigen presentation by MHC class II molecules
SM Weenink, AM Gautam - Immunology and cell biology, 1997 - Wiley Online Library
The tremendous explosion in the field of MHC research in the last 5 years has significantly
advanced our understanding of antigen processing pathways, particularly with regard to …
advanced our understanding of antigen processing pathways, particularly with regard to …
The TCR Vβ signature of bacterial superantigens spreads with stimulus strength
Superantigens (Sags) induce large-scale stimulation of T lymphocytes by a mechanism
distinct from conventional antigen presentation, involving direct MHC binding and …
distinct from conventional antigen presentation, involving direct MHC binding and …
HLA‐DR polymorphisms influence in vivo responses to staphylococcal toxic shock syndrome toxin‐1 in a transgenic mouse model
A Krogman, A Tilahun, CS David, VR Chowdhary… - Hla, 2017 - Wiley Online Library
Toxic shock syndrome toxin‐1 (TSST‐1) is a potent superantigen produced by
Staphylococcus aureus. In addition to menstrual and nonmenstrual toxic shock syndromes …
Staphylococcus aureus. In addition to menstrual and nonmenstrual toxic shock syndromes …
Superantigens of Gram-positive bacteria: structure—function analyses and their implications for biological activity
M Kotb - Current Opinion in Microbiology, 1998 - Elsevier
Just as we thought that we know everything about superantigens, new molecular and
structural studies indicate that we have only just begun to unravel the secrets of these …
structural studies indicate that we have only just begun to unravel the secrets of these …
Selective binding of bacterial toxins to major histocompatibility complex class II-expressing cells is controlled by invariant chain and HLA-DM
PM Lavoie, J Thibodeau, I Cloutier… - Proceedings of the …, 1997 - National Acad Sciences
Bacterial superantigens (SAgs) bind to major histocompatibility complex (MHC) class II
molecules and activate T cells in a Vβ-restricted fashion. We recently identified subsets of …
molecules and activate T cells in a Vβ-restricted fashion. We recently identified subsets of …
Allelic polymorphisms at the H-2A and HLA-DQ loci influence the response of murine lymphocytes to the Mycoplasma arthritidis superantigen MAM
BC Cole, AD Sawitzke, EA Ahmed, CL Atkin… - Infection and …, 1997 - Am Soc Microbiol
Mycoplasma arthritidis, an agent of rodent arthritis, produces a potent superantigen (SAg),
MAM. Previous work established that MAM is presented to T cells by murine H-2E or the …
MAM. Previous work established that MAM is presented to T cells by murine H-2E or the …