Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms

PD Cani, C Depommier, M Derrien, A Everard… - Nature Reviews …, 2022 - nature.com
Ever since Akkermansia muciniphila was discovered and characterized two decades ago,
numerous studies have shown that the lack or decreased abundance of this commensal …

[HTML][HTML] Epidemiology of sarcopenia: Prevalence, risk factors, and consequences

S Yuan, SC Larsson - Metabolism, 2023 - Elsevier
Sarcopenia is a geriatric condition featured by a progressive loss of muscle mass and
function and associated with various adverse health outcomes. In this review, we aimed to …

Cellular senescence: a key therapeutic target in aging and diseases

L Zhang, LE Pitcher, MJ Yousefzadeh… - The Journal of …, 2022 - Am Soc Clin Investig
Cellular senescence is a hallmark of aging defined by stable exit from the cell cycle in
response to cellular damage and stress. Senescent cells (SnCs) can develop a …

The landscape of aging

Y Cai, W Song, J Li, Y Jing, C Liang, L Zhang… - Science China Life …, 2022 - Springer
Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

Taurine deficiency as a driver of aging

P Singh, K Gollapalli, S Mangiola, D Schranner… - Science, 2023 - science.org
Aging is associated with changes in circulating levels of various molecules, some of which
remain undefined. We find that concentrations of circulating taurine decline with aging in …

SARS-CoV-2, COVID-19 and the aging immune system

JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …

A wireless patch for the monitoring of C-reactive protein in sweat

J Tu, J Min, Y Song, C Xu, J Li, J Moore… - Nature biomedical …, 2023 - nature.com
The quantification of protein biomarkers in blood at picomolar-level sensitivity requires
labour-intensive incubation and washing steps. Sensing proteins in sweat, which would …

[HTML][HTML] New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary

T Schmauck-Medina, A Molière, S Lautrup… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Genomic instability, telomere attrition, epigenetic alterations, mitochondrial dysfunction, loss
of proteostasis, deregulated nutrient-sensing, cellular senescence, stem cell exhaustion …

Immune ageing at single-cell resolution

DA Mogilenko, I Shchukina, MN Artyomov - Nature Reviews …, 2022 - nature.com
Ageing leads to profound alterations in the immune system and increases susceptibility to
some chronic, infectious and autoimmune diseases. In recent years, widespread application …

Inorganic nanomaterials with rapid clearance for biomedical applications

X Wang, X Zhong, J Li, Z Liu, L Cheng - Chemical Society Reviews, 2021 - pubs.rsc.org
Inorganic nanomaterials that have inherently exceptional physicochemical properties (eg,
catalytic, optical, thermal, electrical, or magnetic performance) that can provide desirable …