Immune ageing at single-cell resolution
Ageing leads to profound alterations in the immune system and increases susceptibility to
some chronic, infectious and autoimmune diseases. In recent years, widespread application …
some chronic, infectious and autoimmune diseases. In recent years, widespread application …
Hallmarks of T cell aging
M Mittelbrunn, G Kroemer - Nature immunology, 2021 - nature.com
The aged adaptive immune system is characterized by progressive dysfunction as well as
increased autoimmunity. This decline is responsible for elevated susceptibility to infection …
increased autoimmunity. This decline is responsible for elevated susceptibility to infection …
Inorganic nanomaterials with rapid clearance for biomedical applications
Inorganic nanomaterials that have inherently exceptional physicochemical properties (eg,
catalytic, optical, thermal, electrical, or magnetic performance) that can provide desirable …
catalytic, optical, thermal, electrical, or magnetic performance) that can provide desirable …
Immunosenescence: molecular mechanisms and diseases
Z Liu, Q Liang, Y Ren, C Guo, X Ge, L Wang… - Signal transduction and …, 2023 - nature.com
Infection susceptibility, poor vaccination efficacy, age-related disease onset, and neoplasms
are linked to innate and adaptive immune dysfunction that accompanies aging (known as …
are linked to innate and adaptive immune dysfunction that accompanies aging (known as …
[HTML][HTML] Therapeutic application of quercetin in aging-related diseases: SIRT1 as a potential mechanism
Z Cui, X Zhao, FK Amevor, X Du, Y Wang, D Li… - Frontiers in …, 2022 - frontiersin.org
Quercetin, a naturally non-toxic flavonoid within the safe dose range with antioxidant, anti-
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …
Immunosenescence and inflammaging in the aging process: age-related diseases or longevity?
During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …
A review on metal-and metal oxide-based nanozymes: properties, mechanisms, and applications
Q Liu, A Zhang, R Wang, Q Zhang, D Cui - Nano-micro letters, 2021 - Springer
Since the ferromagnetic (Fe 3 O 4) nanoparticles were firstly reported to exert enzyme-like
activity in 2007, extensive research progress in nanozymes has been made with deep …
activity in 2007, extensive research progress in nanozymes has been made with deep …
Restoring metabolism of myeloid cells reverses cognitive decline in ageing
Ageing is characterized by the development of persistent pro-inflammatory responses that
contribute to atherosclerosis, metabolic syndrome, cancer and frailty,–. The ageing brain is …
contribute to atherosclerosis, metabolic syndrome, cancer and frailty,–. The ageing brain is …
Immune-boosting role of vitamins D, C, E, zinc, selenium and omega-3 fatty acids: Could they help against COVID-19?
The world is currently in the grips of the coronavirus disease (COVID-19) pandemic, caused
by the SARS-CoV-2 virus, which has mutated to allow human-to-human spread. Infection …
by the SARS-CoV-2 virus, which has mutated to allow human-to-human spread. Infection …
[HTML][HTML] Why does COVID-19 disproportionately affect older people?
AL Mueller, MS McNamara, DA Sinclair - Aging (albany NY), 2020 - ncbi.nlm.nih.gov
The severity and outcome of coronavirus disease 2019 (COVID-19) largely depends on a
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …