Cellular senescence in knee osteoarthritis: molecular mechanisms and therapeutic implications
J Xie, Y Wang, L Lu, L Liu, X Yu, F Pei - Ageing research reviews, 2021 - Elsevier
Cellular senescence is the inability of cells to proliferate, which has both beneficial and
detrimental effects on tissue development and homeostasis. Chronic accumulation of …
detrimental effects on tissue development and homeostasis. Chronic accumulation of …
[HTML][HTML] Effects of dietary patterns on biomarkers of inflammation and immune responses: a systematic review and meta-analysis of randomized controlled trials
L Koelman, CE Rodrigues, K Aleksandrova - Advances in Nutrition, 2022 - Elsevier
Altered immune cell phenotype and chronic inflammation are key features shared by various
chronic diseases. Evidence from nutritional interventions aimed at alleviating inflammation …
chronic diseases. Evidence from nutritional interventions aimed at alleviating inflammation …
COPD and multimorbidity: recognising and addressing a syndemic occurrence
Most patients with chronic obstructive pulmonary disease (COPD) have at least one
additional, clinically relevant chronic disease. Those with the most severe airflow obstruction …
additional, clinically relevant chronic disease. Those with the most severe airflow obstruction …
Plasma metabolites to profile pathways in noncommunicable disease multimorbidity
M Pietzner, ID Stewart, J Raffler, KT Khaw… - Nature medicine, 2021 - nature.com
Multimorbidity, the simultaneous presence of multiple chronic conditions, is an increasing
global health problem and research into its determinants is of high priority. We used …
global health problem and research into its determinants is of high priority. We used …
Molecular mechanisms of inflammation in sarcopenia: diagnosis and therapeutic update
GE Jimenez-Gutierrez, LE Martínez-Gómez… - Cells, 2022 - mdpi.com
Sarcopenia is generally an age-related condition that directly impacts the quality of life. It is
also related to chronic diseases such as metabolic dysfunction associated with diabetes and …
also related to chronic diseases such as metabolic dysfunction associated with diabetes and …
Immunosenescence, inflammaging, and frailty: role of myeloid cells in age-related diseases
A Bleve, F Motta, B Durante, C Pandolfo… - Clinical reviews in …, 2022 - Springer
The immune system is the central regulator of tissue homeostasis, ensuring tissue
regeneration and protection against both pathogens and the neoformation of cancer cells. Its …
regeneration and protection against both pathogens and the neoformation of cancer cells. Its …
Skeletal muscle oxidative stress and inflammation in aging: Focus on antioxidant and anti-inflammatory therapy
M Chen, Y Wang, S Deng, Z Lian, K Yu - Frontiers in Cell and …, 2022 - frontiersin.org
With aging, the progressive loss of skeletal muscle will have negative effect on multiple
physiological parameters, such as exercise, respiration, thermoregulation, and metabolic …
physiological parameters, such as exercise, respiration, thermoregulation, and metabolic …
Preeclampsia pathophysiology and adverse outcomes during pregnancy and postpartum
Background Preeclampsia is a disease with far-reaching consequences that extend beyond
the immediate postpartum period and have a significant impact later in life. Preeclampsia …
the immediate postpartum period and have a significant impact later in life. Preeclampsia …
Plasmalogens and chronic inflammatory diseases
It is becoming widely acknowledged that lipids play key roles in cellular function, regulating
a variety of biological processes. Lately, a subclass of glycerophospholipids, namely …
a variety of biological processes. Lately, a subclass of glycerophospholipids, namely …
N-Acetylcysteine: A potential therapeutic agent for SARS-CoV-2
FL Poe, J Corn - Medical hypotheses, 2020 - Elsevier
COVID-19, a respiratory disease caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2), continues to spread across the globe. Predisposing factors such as age …
2 (SARS-CoV-2), continues to spread across the globe. Predisposing factors such as age …