ABSTRACT Introduction The 1, 2, 3-triazole ring occupies an important space in medicinal
chemistry due to its unique structural properties, synthetic versatility and pharmacological …

Chroman-4-one scaffold is a privileged structure in heterocyclic chemistry and drug
discovery. Also, chroman-4-ones are important intermediates and interesting building blocks …

The copper‐catalyzed azide–alkyne cycloaddition (CuAAC) reaction has proven to be a
pivotal advance in chemical ligation strategies with applications ranging from polymer …

Tuberculosis is a contagious disease with comparatively high mortality worldwide. The
statistics shows that around three million people throughout the world die annually from …

A metal‐free three‐component reaction to synthesize 1, 4, 5‐trisubstituted 1, 2, 3‐triazoles
from readily available building blocks, such as aldehydes, nitroalkanes, and organic azides …

Tuberculosis (TB) is a highly contagious airborne disease with nearly 25% of the world's
population infected with it. Challenges such as multi drug resistant TB (MDR-TB), extensive …

The cyclooxygenase-2 receptor is a therapeutic target for planning potential drugs with anti-
inflammatory activity. The selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib was …

Epilepsy is one of the common diseases seriously threatening life and health of human.
More than 50 million people are suffering from this condition and anticonvulsant agents are …

Alzheimer's disease (AD) is a detrimental neurodegenerative disease that progressively
worsens with time. Clinical options are limited and only provide symptomatic relief to AD …

Cancer is a class of formidable disease with high degree of mortality. Despite much
progress in chemotherapy, the problem of drug resistance has led to the search for newer …