In the present work, a new series of imidazo [1, 2-a] pyrimidine Schiff base derivatives have
been obtained using an easy and conventional synthetic route. The synthesized compounds …

A series of novel triazole nucleobase analogues containing steroidal/coumarin/quinoline
moieties have been synthesized based on copper-catalyzed azide-alkyne cycloaddition …

A series of 3-(triazolyl)-coumarins were synthesized and tested as anti-inflammatory agents.
It was possible to infer that these compounds do not alter the interaction of LPS with TLR-4 …

The key functions of microtubules and the mitotic spindle in cell division make them
attractive targets for cancer therapy. In this study, a series of 1-(benzofuran-3-yl)-4-(3, 4, 5 …

Introduction The unique physicochemical properties and chemical diversity of
organofluorine compounds have remarkably contributed for their wide utility in the area of …

A novel series of analogues based on 5-(1-(4-chloro-3-methoxyphenyl) piperidin-4-yl)-4-
phenyl-2 H-1, 2, 4-triazole-3 (4 H)-thione core have been synthesized and their potential as …

Quinazolinone scaffold has been considered as a magic moiety possessing myriad
spectrum of medicinal activities. Diversity of biological response profile has attracted …

The worldwide problem of microbial resistance has drawn utmost attention for medicinal
chemists because of failure of currently available antimicrobial therapy against microbial …

Triazole is a valuable platform in medicinal chemistry, possessing assorted pharmacological
properties, which could play a major role in the common mechanisms associated with …

The click azide= alkyne 1, 3-dipolar cycloaddition (click chemistry) has become the
approach of choice for bioconjugations in medicinal chemistry, providing facile reaction …