Lymph nodes are the most common sites of metastasis in cancer patients. Nodal disease
status provides great prognostic power, but how lymph node metastases should be treated …

G protein coupled receptors (GPCRs) are a class of membrane proteins that sense
extracellular signals ranging from light to odorants and small molecules and activate …

Rationale: Malignant ascites in peritoneal metastases is a lipid-enriched microenvironment
and is frequently involved in the poor prognosis of epithelial ovarian cancer (EOC) …

The recent outbreak of Zika virus (ZIKV) was associated with birth defects and pregnancy
loss when maternal infection occurs in early pregnancy, but specific mechanisms driving …

Glucose transporters (GLUTs) are essential for organism-wide glucose homeostasis in
mammals, and their dysfunction is associated with numerous diseases, such as diabetes …

Dietary restriction (DR) delays aging and the onset of age-associated diseases. However, it
is yet to be determined whether and how restriction of specific nutrients promote longevity …

Over the decades, a variety of chemically synthesized drugs are being used to cure existing
diseases but often these drugs could not be effectively employed for the treatment of serious …

PIEZO1 is a mechanosensitive channel widely presented in eukaryotic organisms. Although
the PIEZO family was discovered in 2010, main questions related to the molecular structure …

During the storage, fish oil is susceptible to peroxidation to form toxic lipid derivatives,
dietary intake of oxidized fish oil would induce oxidative stress and inflammation in animals …

Pancreatic β-cell failure and death contribute significantly to the pathogenesis of type 2
diabetes. One of the main factors responsible for β-cell dysfunction and subsequent cell …