Bloodstream infections in critically ill patients: an expert statement
Bloodstream infection (BSI) is defined by positive blood cultures in a patient with systemic
signs of infection and may be either secondary to a documented source or primary—that is …
signs of infection and may be either secondary to a documented source or primary—that is …
Diagnosis and treatment of invasive candidiasis
N Barantsevich, E Barantsevich - Antibiotics, 2022 - mdpi.com
Candida species, belonging to commensal microbial communities in humans, cause
opportunistic infections in individuals with impaired immunity. Pathogens encountered in …
opportunistic infections in individuals with impaired immunity. Pathogens encountered in …
EORTC/MSGERC definitions of invasive fungal diseases: summary of activities of the intensive care unit working group
M Bassetti, E Azoulay, BJ Kullberg… - Clinical Infectious …, 2021 - academic.oup.com
The EORTC/MSGERC recently revised and updated the consensus definitions of invasive
fungal disease (IFD). These definitions primarily focus on patients with cancer and stem cell …
fungal disease (IFD). These definitions primarily focus on patients with cancer and stem cell …
Initial antimicrobial management of sepsis
Sepsis is a common consequence of infection, associated with a mortality rate> 25%.
Although community-acquired sepsis is more common, hospital-acquired infection is more …
Although community-acquired sepsis is more common, hospital-acquired infection is more …
Timing of antibiotic therapy in the ICU
Severe or life threatening infections are common among patients in the intensive care unit
(ICU). Most infections in the ICU are bacterial or fungal in origin and require antimicrobial …
(ICU). Most infections in the ICU are bacterial or fungal in origin and require antimicrobial …
Antifungal drug resistance: an emergent health threat
A Vitiello, F Ferrara, M Boccellino, A Ponzo, C Cimmino… - Biomedicines, 2023 - mdpi.com
Fungal infections, named mycosis, can cause severe invasive and systemic diseases that
can even lead to death. In recent years, epidemiological data have recorded an increase in …
can even lead to death. In recent years, epidemiological data have recorded an increase in …
Invasive candidiasis in critical care: challenges and future directions
C Logan, I Martin-Loeches, T Bicanic - Intensive care medicine, 2020 - Springer
Invasive candidiasis is the most common critical care-associated fungal infection with a
crude mortality of~ 40–55%. Important factors contributing to risk of invasive candidiasis in …
crude mortality of~ 40–55%. Important factors contributing to risk of invasive candidiasis in …
(1 → 3)-β-d-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trial
F Bloos, J Held, S Kluge, P Simon, K Kogelmann… - Intensive care …, 2022 - Springer
Purpose To investigate whether (1→ 3)-β-d-Glucan (BDG)-guidance shortens time to
antifungal therapy and thereby reduces mortality of sepsis patients with high risk of invasive …
antifungal therapy and thereby reduces mortality of sepsis patients with high risk of invasive …
Epidemiology of Candidemia and Fluconazole Resistance in an ICU before and during the COVID-19 Pandemic Era
The objectives of this study were to investigate the incidence of candidemia, as well as the
factors associated with Candida species distribution and fluconazole resistance, among …
factors associated with Candida species distribution and fluconazole resistance, among …
ICU-acquired infections in immunocompromised patients
Immunocompromised patients account for an increasing proportion of the typical intensive
care unit (ICU) case-mix. Because of the increased availability of new drugs for cancer and …
care unit (ICU) case-mix. Because of the increased availability of new drugs for cancer and …