[HTML][HTML] Flavonoids in cancer and apoptosis

M Abotaleb, SM Samuel, E Varghese, S Varghese… - Cancers, 2018 - mdpi.com
Cancer is the second leading cause of death globally. Although, there are many different
approaches to cancer treatment, they are often painful due to adverse side effects and are …

Apigenin: A dietary flavonoid with diverse anticancer properties

J Madunić, IV Madunić, G Gajski, J Popić… - Cancer letters, 2018 - Elsevier
Apigenin is a natural flavonoid found in several dietary plant foods such as vegetables and
fruits. A large number of studies conducted over the past years have shown that this …

[HTML][HTML] Transcription factor C/EBP homologous protein in health and diseases

Y Yang, L Liu, I Naik, Z Braunstein, J Zhong… - Frontiers in …, 2017 - frontiersin.org
C/EBP homologous protein (CHOP), known also as DNA damage-inducible transcript 3 and
as growth arrest and DNA damage-inducible protein 153 (GADD153), is induced in …

[HTML][HTML] Does oral apigenin have real potential for a therapeutic effect in the context of human gastrointestinal and other cancers?

EF DeRango-Adem, J Blay - Frontiers in pharmacology, 2021 - frontiersin.org
Apigenin (4′, 5, 7-trihydroxyflavone) is a plant flavone that has been found to have various
actions against cancer cells. We evaluated available evidence to determine whether it is …

[HTML][HTML] Apigenin as tumor suppressor in cancers: Biotherapeutic activity, nanodelivery, and mechanisms with emphasis on pancreatic cancer

M Ashrafizadeh, MR Bakhoda, Z Bahmanpour… - Frontiers in …, 2020 - frontiersin.org
Pancreatic cancer is the most lethal malignancy of the gastrointestinal tract. Due to its
propensity for early local and distant spread, affected patients possess extremely poor …

Rosemary (Rosmarinus officinalis L.): extraction techniques, analytical methods and health-promoting biological effects

S Lešnik, V Furlan, U Bren - Phytochemistry Reviews, 2021 - Springer
Rosemary (Rosmarinus officinalis L.) of the Lamiaceae family represents an evergreen
medicinal plant with various health-promoting pharmacological effects. This paper provides …

[HTML][HTML] Enzymatic metabolism of flavonoids by gut microbiota and its impact on gastrointestinal cancer

RK Al-Ishaq, A Liskova, P Kubatka, D Büsselberg - Cancers, 2021 - mdpi.com
Simple Summary Flavonoid's consumption is reported to impact GI cancer progression
positively. As 90% of flavonoids consumed, undergo metabolism and conversion by the …

[HTML][HTML] Apigenin induces autophagy and cell death by targeting EZH2 under hypoxia conditions in gastric cancer cells

TW Kim, HG Lee - International Journal of Molecular Sciences, 2021 - mdpi.com
Hypoxia is a major obstacle to gastric cancer (GC) therapy and leads to chemoresistance as
GC cells are frequently exposed to the hypoxia environment. Apigenin, a flavonoid found in …

Flavonoids as promising anticancer therapeutics: Contemporary research, nanoantioxidant potential, and future scope

M Gupta, J Ahmad, J Ahamad, S Kundu… - Phytotherapy …, 2023 - Wiley Online Library
Flavonoids are natural polyphenolic compounds considered safe, pleiotropic, and readily
available molecules. It is widely distributed in various food products such as fruits and …

Flavonoids nanostructures promising therapeutic efficiencies in colorectal cancer

S Hassani, H Maghsoudi, F Fattahi… - International Journal of …, 2023 - Elsevier
Colorectal cancer is among the frequently diagnosed cancers with high mortality rates
around the world. Polyphenolic compounds such as flavonoids are secondary plant …