[HTML][HTML] Understanding the role of neutrophils in acute respiratory distress syndrome
Acute respiratory distress syndrome (ARDS) is difficult to treat and is associated with a high
mortality rate. The most severe form of coronavirus disease 2019 (COVID-19) also leads to …
mortality rate. The most severe form of coronavirus disease 2019 (COVID-19) also leads to …
Oxidative stress and inflammation in acute and chronic lung injuries
FS Bezerra, M Lanzetti, RT Nesi, AC Nagato, CP Silva… - Antioxidants, 2023 - mdpi.com
Acute and chronic lung injuries are among the leading causes of mortality worldwide. Lung
injury can affect several components of the respiratory system, including the airways …
injury can affect several components of the respiratory system, including the airways …
p53: a key protein that regulates pulmonary fibrosis
Q Wu, K Zhang, S Jiang, L Fu, Y Shi… - Oxidative Medicine …, 2020 - Wiley Online Library
Pulmonary fibrosis is a progressively aggravating lethal disease that is a serious public
health concern. Although the incidence of this disease is increasing, there is a lack of …
health concern. Although the incidence of this disease is increasing, there is a lack of …
A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip
A Sengupta, A Dorn, M Jamshidi, M Schwob… - Frontiers in …, 2023 - frontiersin.org
Prolonged exposure to environmental respirable toxicants can lead to the development and
worsening of severe respiratory diseases such as asthma, chronic obstructive pulmonary …
worsening of severe respiratory diseases such as asthma, chronic obstructive pulmonary …
[HTML][HTML] Polyhexamethylene guanidine phosphate increases stress granule formation in human 3D lung organoids under respiratory syncytial virus infection
Polyhexamethylene guanidine phosphate (PHMG-p), a humidifier disinfectant, is known to
cause lung toxicity, including inflammation and pulmonary fibrosis. In this study, we aimed to …
cause lung toxicity, including inflammation and pulmonary fibrosis. In this study, we aimed to …
HIWI2 induces G2/M cell cycle arrest and apoptosis in human fibrosarcoma via the ROS/DNA damage/p53 axis
Aims Piwi-like RNA-mediated gene silencing 4 (PIWIL4) or HIWI2, are seen deregulated in
human cancers and possibly play critical roles in tumorigenesis. It is unknown what role …
human cancers and possibly play critical roles in tumorigenesis. It is unknown what role …
Autophagy-dependent cell cycle arrest in esophageal cancer cells exposed to dihydroartemisinin
Q Ma, H Liao, L Xu, Q Li, J Zou, R Sun, D Xiao, C Liu… - Chinese Medicine, 2020 - Springer
Background Dihydroartemisinin (DHA), a derivate of artemisinin, is an effective antimalarial
agent. DHA has been shown to exert anticancer activities to numerous cancer cells in the …
agent. DHA has been shown to exert anticancer activities to numerous cancer cells in the …
Critical window of exposure of CMIT/MIT with respect to developmental effects on zebrafish embryos: Multi-level endpoint and proteomics analysis
Systemic toxicity, particularly, developmental defects of humidifier disinfectant chemicals that
have caused lung injuries in Korean children, remains to be elucidated. This study …
have caused lung injuries in Korean children, remains to be elucidated. This study …
Evaluation of polyhexamethylene guanidine-induced lung injuries by chest CT, pathologic examination, and RNA sequencing in a rat model
Our aim was to correlate chest CT and pathologic findings of polyhexamethylene guanidine
phosphate (PHMG)-induced lung injuries in a rat model, to determine whether PHMG …
phosphate (PHMG)-induced lung injuries in a rat model, to determine whether PHMG …
Evaluation of the long-term effect of polyhexamethylene guanidine phosphate in a rat lung model using conventional chest computed tomography with histopathologic …
There have been no studies on the effects of polyhexamethylene guanidine phosphate
(PHMG) after a long period of exposure in the rodent model. We aimed to evaluate long-term …
(PHMG) after a long period of exposure in the rodent model. We aimed to evaluate long-term …