[HTML][HTML] Stimuli-activatable nanomedicine meets cancer theranostics

H Li, Y Feng, Q Luo, Z Li, X Li, H Gan, Z Gu, Q Gong… - Theranostics, 2023 - ncbi.nlm.nih.gov
Stimuli-activatable strategies prevail in the design of nanomedicine for cancer theranostics.
Upon exposure to endogenous/exogenous stimuli, the stimuli-activatable nanomedicine …

Activatable nano-photosensitizers for precise photodynamic cancer therapy

Z Li, Z Zhou, Y Wang, J Wang, L Zhou… - Coordination Chemistry …, 2023 - Elsevier
Owing to the excellent cell ablation ability and low side effects, photodynamic therapy (PDT)
plays an important role in disease treatment, especially cancer. However, most PDT agents …

Cuproptosis induced by ROS responsive nanoparticles with elesclomol and copper combined with αPD‐L1 for enhanced cancer immunotherapy

B Guo, F Yang, L Zhang, Q Zhao, W Wang… - Advanced …, 2023 - Wiley Online Library
Cuproptosis is a new cell death that depends on copper (Cu) ionophores to transport Cu into
cancer cells, which induces cell death. However, existing Cu ionophores are small …

Ultra‐Small High‐Entropy Alloy Nanoparticles: Efficient Nanozyme for Enhancing Tumor Photothermal Therapy

Y Ai, MQ He, H Sun, X Jia, L Wu, X Zhang… - Advanced …, 2023 - Wiley Online Library
High‐entropy alloys nanoparticles (HEANPs) are receiving extensive attention due to their
broad compositional tunability and unlimited potential in bioapplication. However …

Biodegradable NIR‐II Pseudo Conjugate Polymeric Nanoparticles Amplify Photodynamic Immunotherapy via Alleviation of Tumor Hypoxia and Tumor‐Associated …

J Wan, X Zhang, D Tang, T Liu, H Xiao - Advanced Materials, 2023 - Wiley Online Library
Photodynamic therapy (PDT) has achieved great success in cancer treatment. Despite its
great promise, the efficacy of photodynamic immunotherapy can be limited by the hypoxia in …

Recent progress in NIR-II fluorescence imaging-guided drug delivery for cancer theranostics

S Roy, N Bag, S Bardhan, I Hasan, B Guo - Advanced drug delivery reviews, 2023 - Elsevier
Fluorescence imaging in the second near-infrared window (NIR-II) has become a prevalent
choice owing to its appealing advantages like deep penetration depth, low …

Bioorthogonal Guided Activation of cGAS‐STING by AIE Photosensitizer Nanoparticles for Targeted Tumor Therapy and Imaging

M Cui, D Tang, B Wang, H Zhang, G Liang… - Advanced …, 2023 - Wiley Online Library
Photodynamic therapy (PDT) and photothermal therapy (PTT) leverage reactive oxygen
species (ROS) and control local hyperthermia by photosensitizer to perturb intracellular …

Tetrahedral DNA Nanostructure with Interferon Stimulatory DNA Delivers Highly Potent Toxins and Activates the cGAS‐STING Pathway for Robust Chemotherapy and …

L Zhang, Y Wang, J Karges, D Tang… - Advanced …, 2023 - Wiley Online Library
Tumor metastases and reoccurrences are considered the leading cause of cancer‐
associated deaths. While highly efficient treatments for the eradication of primary tumors …

A NIR‐II Fluorescent PolyBodipy Delivering Cationic Pt‐NHC with Type II Immunogenic Cell Death for Combined Chemotherapy and Photodynamic Immunotherapy

B Wang, D Tang, J Karges, M Cui… - Advanced Functional …, 2023 - Wiley Online Library
Tumor immunotherapy has emerged as one of the most promising clinical techniques to
treat cancer tumors. Despite its clinical application, the cancerous immunosuppressive …

NIR‐II Light Accelerated Prodrug Reduction of Pt (IV)‐Incorporating Pseudo Semiconducting Polymers for Robust Degradation and Maximized Photothermal/Chemo …

D Tang, H Zhou, M Cui, G Liang, H Zhang… - Advanced …, 2023 - Wiley Online Library
Selective activation of Pt (IV) prodrugs within tumors is particularly attractive because of their
low damage to normal tissues. However, current common activation via chemical …