Ischemic stroke is the leading cause of death and disability worldwide, and restoring the
blood flow to ischemic brain tissues is currently the main therapeutic strategy. However …

The α7 nicotinic acetylcholine receptor (α7nAChR) has been studied for many years since
its discovery. Although many functions and characteristics of brain α7nAChR are widely …

Cerebral ischemia/reperfusion (CIR) injury occurs when blood flow is restored in the brain,
causing secondary damage to the ischemic tissues. Previous studies have shown that …

Background: Ischemia/reperfusion (I/R) caused by ischemic stroke treatments leads to brain
injury, and autophagy plays a role in the pathology. Astragaloside IV is a potential …

Eugenol, as an active compound isolated from Acorus gramineus, has been shown to
protect against cerebral ischemia-reperfusion (I/R) injury. Nonetheless, the detailed …

Autophagy is crucial for maintaining cellular homeostasis, and can be activated after
ischemic stroke. It also participates in nerve injury and repair. The purpose of this study was …

Background. A substantial increase in histone deacetylase 3 (HDAC3) expression is
implicated in the pathological process of diabetes and stroke. However, it is unclear whether …

Background There is evidence that remote limb ischemic postconditioning (RIPostC) can
reduce ischemia-reperfusion injury (IRI) and improve the prognosis of patients with ischemic …

Ischemic stroke triggers a series of complex pathophysiological processes including
autophagy. Differential activation of autophagy occurs in neurons derived from males versus …

Stroke is a main cause of disability and death among adults in China, and acute ischemic
stroke accounts for 80% of cases. The key to ischemic stroke treatment is to recanalize the …