Periodontitis is an inflammatory disease involving the destruction of both soft and hard tissue
in the periodontal region. Although dysbiosis of the local microbial community initiates local …

Periodontitis, or gum disease, affects millions of people each year. Although it is associated
with a defined microbial composition found on the surface of the tooth and tooth root, the …

Observations from numerous clinical, epidemiological and serological studies link
periodontitis with severity and progression of rheumatoid arthritis. The strong association is …

Objective: The aim of the study is to estimate the salivary TNF-α in chronic and aggressive
periodontitis and control participants and further correlate the levels with clinical parameter …

Background: Macrophages are central players in the pathogenesis of periodontitis.
However, the phenotypic switch of macrophage M1/M2 remains uncertain. Methods: Adult …

The presence of periodontal diseases (PDs) often strongly correlates with other severe
chronic inflammatory conditions, including cardiovascular disease, diabetes, and arthritis …

Inflammation plays a crucial role in the onset and development of atherosclerosis.
Periodontitis is a common chronic disease linked to other chronic inflammatory diseases …

Background: Periodontitis has been associated with a moderate systemic inflammatory
response. Successful periodontal therapy could decrease serum inflammatory parameters …

Objective Although accumulating evidence indicates that macrophages are central players
in the destructive and reparative phases of periodontal disease, their polarization states at …

Background: Current publications present contradictory findings regarding interleukin-8 (IL-
8) levels in patients with chronic periodontitis (CP). This systematic review compile …