Tools and strategies of systems metabolic engineering for the development of microbial cell factories for chemical production

YS Ko, JW Kim, JA Lee, T Han, GB Kim… - Chemical Society …, 2020 - pubs.rsc.org
Sustainable production of chemicals from renewable non-food biomass has become a
promising alternative to overcome environmental issues caused by our heavy dependence …

A comprehensive metabolic map for production of bio-based chemicals

SY Lee, HU Kim, TU Chae, JS Cho, JW Kim, JH Shin… - Nature …, 2019 - nature.com
Production of industrial chemicals using renewable biomass feedstock is becoming
increasingly important to address limited fossil resources, climate change and other …

Flavonoid biosynthetic pathways in plants: Versatile targets for metabolic engineering

SM Nabavi, D Šamec, M Tomczyk, L Milella… - Biotechnology …, 2020 - Elsevier
Plants, fungi, and microorganisms are equipped with biosynthesis machinery for producing
thousands of secondary metabolites. These compounds have important functions in nature …

Metabolic engineering of Escherichia coli for natural product biosynthesis

D Yang, SY Park, YS Park, H Eun, SY Lee - Trends in Biotechnology, 2020 - cell.com
Natural products are widely employed in our daily lives as food additives, pharmaceuticals,
nutraceuticals, and cosmetic ingredients, among others. However, their supply has often …

[HTML][HTML] Pseudomonas putida as a functional chassis for industrial biocatalysis: from native biochemistry to trans-metabolism

PI Nikel, V de Lorenzo - Metabolic engineering, 2018 - Elsevier
The itinerary followed by Pseudomonas putida from being a soil-dweller and plant colonizer
bacterium to become a flexible and engineer-able platform for metabolic engineering stems …

Systems metabolic engineering strategies: integrating systems and synthetic biology with metabolic engineering

KR Choi, WD Jang, D Yang, JS Cho, D Park… - Trends in …, 2019 - cell.com
Metabolic engineering allows development of microbial strains efficiently producing
chemicals and materials, but it requires much time, effort, and cost to make the strains …

Phytostilbenes as agrochemicals: Biosynthesis, bioactivity, metabolic engineering and biotechnology

P Jeandet, A Vannozzi, E Sobarzo-Sánchez… - Natural product …, 2021 - pubs.rsc.org
Covering: 1976 to 2020. Although constituting a limited chemical family, phytostilbenes
represent an emblematic group of molecules among natural compounds. Ever since their …

Recent advances in modular co-culture engineering for synthesis of natural products

R Wang, S Zhao, Z Wang, MAG Koffas - Current Opinion in Biotechnology, 2020 - Elsevier
Highlights•Modular co-culture engineering for the production of natural
products.•Advantages of modular co-culture engineering in the field of …

Synthetic biology and metabolic engineering of actinomycetes for natural product discovery

E Palazzotto, Y Tong, SY Lee, T Weber - Biotechnology Advances, 2019 - Elsevier
Actinomycetes are one of the most valuable sources of natural products with industrial and
medicinal importance. After more than half a century of exploitation, it has become …

[HTML][HTML] Modular engineering for microbial production of carotenoids

C Li, CA Swofford, AJ Sinskey - Metabolic Engineering Communications, 2020 - Elsevier
There is an increasing demand for carotenoids due to their applications in the food, flavor,
pharmaceutical and feed industries, however, the extraction and synthesis of these …