Asthma has been considered a T helper 2 (TH2) cell-associated inflammatory disease, and
TH2-type cytokines, such as interleukin-4 (IL-4), IL-5 and IL-13, are thought to drive the …

Advances have been made in defining the mechanisms for the control of allergic airway
inflammation in response to inhaled antigens. Several genes, including ADAM33, DPP10 …

Ferroptosis, an iron-dependent form of regulated cell death, was recently demonstrated to
be closely associated with the immune system. Regulators of ferroptosis may be the cells …

Asthma is a complex trait, often associated with atopy. The genetic contribution has been
evidenced by familial occurrence. Genome-wide association studies allowed for associating …

The benefits of moderate aerobic physical exercise for allergic asthma are well-known,
particularly that of the anti-inflammatory effect that occurs by reducing Th2 responses and …

While it is well established that CD4+ T lymphocytes play a crucial role in the initiation,
progression and persistence of asthma, the role of CD8+ T cells is less understood. CD8+ T …

Background The incidence of asthma is increasing at an alarming rate and while the current
available therapies are effective in the majority of patients they fail to adequately control …

Background DJ-1 is an antioxidant protein known to regulate mast cell–mediated allergic
response, but its role in airway eosinophilic interactions and allergic inflammation is not …

Бронхиальная астмахроническое воспалительное заболевание бронхов, основой
которого является их обратимая обструкция, приводящая к приступам удушья и …

Asthma is a chronic disorder of the airways associated in many instances with structural
changes of the airways, termed airway remodelling. Irritant and allergen‐induced murine …