Expression of acetoacetyl-CoA synthetase, a novel cytosolic ketone body-utilizing enzyme, in human brain
M Ohgami, N Takahashi, M Yamasaki… - Biochemical Pharmacology, 2003 - Elsevier
Acetoacetyl-CoA synthetase (AACS, acetoacetate-CoA ligase, EC 6.2. 1.16) is a ketone
body-utilizing enzyme, the physiological role of which remains unclear yet in mammals …
body-utilizing enzyme, the physiological role of which remains unclear yet in mammals …
[PDF][PDF] Основні механізми виникнення та розвитку діабетичних ускладнень: роль нітративного стресу
ВР Дрель - Біологічні студії, 2010 - scholar.archive.org
В огляді розглянуто основний механізм виникнення оксидативного стресу за участю
електрон-транспортного ланцюга мітохондрій при гіперглікемії. Описано основні …
електрон-транспортного ланцюга мітохондрій при гіперглікемії. Описано основні …
Impaired mitochondrial energy metabolism as a novel risk factor for selective onset and progression of dementia in oldest-old subjects
Recent evidence shows that Alzheimer disease (AD) dementia in the oldest-old subjects
was associated with significantly less amyloid plaque and fibrillary tangle neuropathology …
was associated with significantly less amyloid plaque and fibrillary tangle neuropathology …
Myocardial carnitine palmitoyltransferase I as a target for oxidative modification in inflammation and sepsis
S Eaton, K Fukumoto, G Stefanutti… - Biochemical Society …, 2003 - portlandpress.com
CPT I (outer membrane carnitine palmitoyltransferase I) is a crucial enzyme in myocardial
substrate selection. Two isoforms exist in the heart, the liver (L-) and muscle (M-) isoforms …
substrate selection. Two isoforms exist in the heart, the liver (L-) and muscle (M-) isoforms …
蛋白质酪氨酸硝化的研究
池泉， 黄开勋 - 化学进展, 2006 - manu56.magtech.com.cn
摘要蛋白质酪氨酸硝基化是一种重要的蛋白质翻译后修饰, 与多种病症相关. 经由过氧亚硝酸根(
ONOO-) 和NO2-ΠH2 O2Π 血红素过氧化物酶体系是促使蛋白质硝化最主要的两种途径 …
ONOO-) 和NO2-ΠH2 O2Π 血红素过氧化物酶体系是促使蛋白质硝化最主要的两种途径 …
Growth-inhibitory effects of the ketone body, monoacetoacetin, on human gastric cancer cells with succinyl-CoA: 3-oxoacid CoA-transferase (SCOT) deficiency
M Sawai, M Yashiro, Y Nishiguchi, M Ohira… - Anticancer …, 2004 - ar.iiarjournals.org
Background: Monoacetoacetin (MAA) has been used experimentally as a physiological
energy source in parenteral nutrition. Succinyl-CoA: 3-oxoacid CoA transferase (SCOT) is a …
energy source in parenteral nutrition. Succinyl-CoA: 3-oxoacid CoA transferase (SCOT) is a …
Methamphetamine induces endoplasmic reticulum stress related gene CHOP/Gadd153/ddit3 in dopaminergic cells
Y Irie, M Saeki, H Tanaka, Y Kanemura, S Otake… - Cell and tissue …, 2011 - Springer
We examined the toxicity of methamphetamine and dopamine in CATH. a cells, which were
derived from mouse dopamine-producing neural cells in the central nervous system. Use of …
derived from mouse dopamine-producing neural cells in the central nervous system. Use of …
Effects of age and calorie restriction on tryptophan nitration, protein content, and activity of succinyl-CoA: 3-ketoacid CoA transferase in rat kidney mitochondria
C Brégère, I Rebrin, TK Gallaher, RS Sohal - Free Radical Biology and …, 2010 - Elsevier
This study examined the protein targets of nitration and the consequent impact on protein
function in rat kidney mitochondria at 4, 13, 19, and 24 months of age. Succinyl-CoA …
function in rat kidney mitochondria at 4, 13, 19, and 24 months of age. Succinyl-CoA …
Metallothionein prevents diabetes-induced cardiac pathological changes, likely via the inhibition of succinyl-CoA: 3-ketoacid coenzyme A transferase-1 nitration at …
W Cong, W Ma, T Zhao, Z Zhu… - American Journal …, 2013 - journals.physiology.org
We previously demonstrated that metallothionein (MT)-mediated protection from diabetes-
induced pathological changes in cardiac tissues is related to suppression of superoxide …
induced pathological changes in cardiac tissues is related to suppression of superoxide …
Differential expression of succinyl CoA transferase (SCOT) genes in somatic and germline cells of the mouse testis
H Tanaka, N Iguchi, Y Miyagawa… - … journal of andrology, 2003 - Wiley Online Library
Summary Succinyl CoA: 3‐oxo acid CoA transferase (SCOT/OXCT; EC 2.8. 3.5) is a key
mitochondrial enzyme in the metabolism of ketone bodies in various organs (but not in the …
mitochondrial enzyme in the metabolism of ketone bodies in various organs (but not in the …