Peroxynitrite is involved in the pathogenesis of pulmonary diseases such as asthma,
occupational pulmonary diseases and acute respiratory distress syndrome (ARDS) due to …

Recent findings from septic acute renal injury studies have implicated the mitochondrion as
an important factor in kidney injury, and that increased sympathetic nerve activity may …

In the review described the main mechanisms of the oxidative stress initiation in the
mitochondria electron-transport chain under the hyperglycaemia condition. It is described …

Protein tyrosine nitration, detected as anti-nitrotyrosine immunoreactivity, is considered one
of the most relevant disease biomarkers of oxidative stress. The mechanism of nitration …

BACKGROUND: Bacterial translocation (BT) occurs under stress, and enteral nutrition is
said to be effective in counteracting this effect. The usefulness of iv nutrition of …

线粒体琥珀酰辅酶A 转移酶(SCOT) 含有4 个酪氨酸残基, 其4, 76 位点酪氨酸(Tyr4, Tyr76)
的硝基化可导致其酶活性下降, 制备特定的抗体可对其硝基化水平和位点进行检测 …

Mammalian ketone body metabolism partially oxidizes hepatic acyl-chains to ketone body
intermediates, which can serve as alternative fuels in extrahapetic tissues during …

O LPS é capaz de ativar diferentes células, incluindo plaquetas, causando a liberação de
mediadores inflamatórios como o óxido nítrico, interleucinas e espécies reativas de …

Mitochondrial modulation of cellular bioenergetics has been posited as a mechanism to
explain the apparent paradox between the clinical and biochemical presentation of septic …

Two tyrosine residues (Tyr4 and Tyr76) of succinyl-CoA: 3-oxoacid CoA transferase (SCOT)
are sensitive to nitric oxide (NO) stress, as assessed by mass spectrometry and site-direct …