Aging is associated with the occurrence of diverse degenerative changes in various tissues
and organs and with an increased incidence of neurological disorders, especially …

Animal models are used to better understand the various mechanisms involved in the
pathogenesis of diseases and explore potential pathways that will aid in discovering …

Currently, there is no known cure for neurodegenerative disease. However, the available
therapies aim to manage some of the symptoms of the disease. Human neurodegenerative …

Brain-derived neurotrophic factor (BDNF) is an important modulator for a variety of functions
in the central nervous system (CNS). A wealth of evidence, such as reduced mRNA and …

Brain-derived neurotrophic factor (BDNF) has a crucial function in the central nervous
system and in sensory structures including olfactory and auditory systems. Many studies …

Aims Diabetes mellitus can cause cognitive impairments, a state between normal aging and
dementia. Effective clinical interventions are urgently needed to prevent or treat this …

Rationale: Mitochondrial dysfunction is a key factor in the pathogenesis of Parkinson's
disease (PD). Accordingly, many aspects of mitochondrial function have been studied as a …

Background Peripheral nerve injury (PNI) is a public health concern that results in sensory
and motor disorders as well as neuropathic pain and secondary lesions. Currently, effective …

Parkinson's disease (PD) is a progressive neurodegenerative disorder imposing a severe
health and socioeconomic burden worldwide. Existing pharmacological approaches for …

The pathological role of vitamin K2 in Alzheimer's disease (AD) involves a definite link
between impaired cognitive functions and decreased serum vitamin K levels. Vitamin K2 …