Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …

The advent of immunotherapy, a groundbreaking advancement in cancer treatment, has
given rise to the prominence of the tumor microenvironment (TME) as a critical area of …

The prevalence of Helicobacter pylori (H. pylori) infection has exceeded 50% worldwide,
and it is considered a high-risk factor for chronic gastritis, peptic ulcer, gastric …

As the predominant immunosuppressive component within the tumor microenvironment
(TME), cancer-associated fibroblasts (CAFs) inhibit Natural Killer cell (NK cell) activity to …

Chronic inflammation is linked to carcinogenesis, particularly in the digestive organs, ie, the
stomach, colon, and liver. The mechanism of this effect has, however, only partly been …

According to the 2020 global cancer data released by the World Cancer Research Fund
(WCRF) International, gastric cancer (GC) is the fifth most common cancer worldwide, with …

Background and objective Published studies proved that both pyroptosis and periodontitis
owned a substantial relationship with immunity, and recent research revealed a solid …

The gastrointestinal microbiome has been shown to play a key role in determining the
responses to cancer immunotherapy, including immune checkpoint inhibitor (ICI) therapy …

Although immunotherapy has revolutionized solid tumor treatment, durable responses in
gastric cancer (GC) remain limited. The heterogeneous tumor microenvironment (TME) …

Bacterial infection is a huge threat to the health of human beings and animals. The abuse of
antibiotics has led to the occurrence of bacterial multidrug resistance, which has become a …