Lung cancer is the primary cause of mortality in the United States and around the globe.
Therapeutic options for lung cancer treatment include surgery, radiation therapy …

To redirect T cells against tumor cells, T cells can be engineered ex vivo to express cancer-
antigen specific T cell receptors (TCRs), generating products known as TCR-engineered T …

Tumor-infiltrating lymphocytes (TILs), frontline soldiers of the adaptive immune system, are
recruited into the tumor site to fight against tumors. However, their small number and …

Chimeric antigen receptor (CAR) T cell (CAR-T cell) therapy based on gene editing
technology represents a significant breakthrough in personalized immunotherapy for human …

Nucleic acid-based cancer biomarkers (NABCBs) have emerged as a notable and
continuously captivating research focal point within the domain of oncology. As a result …

Colorectal cancer (CRC) is one of the most devastating diseases that accounts for numerous
deaths worldwide. Tumor cell-autonomous pathways, such as the oncogenic signaling …

Simple Summary Induced pluripotent stem cells (iPSCs) that can be genetically engineered
and differentiated into different types of immune cells, providing an unlimited resource for …

Recent development of methods to discover and engineer therapeutic T‐cell receptors
(TCRs) or antibody mimics of TCRs, and to understand their immunology and …

Recent advances in cancer immunology have enabled the discovery of promising
immunotherapies for various malignancies that have shifted the cancer treatment paradigm …

Adoptive cell therapy with tumor-infiltrating lymphocytes (TIL) is gaining momentum and
demonstrating durable responses in patients with advanced melanoma. Although …