Chemokine receptors have been implicated in a wide range of CNS inflammatory diseases
and have important roles in the recruitment and positioning of immune cells within tissues …

The CCR5 molecule was reported in 1996 as the main HIV‐1 co‐receptor. In that same year,
the CCR5Δ32 genetic variant was described as a strong protective factor against HIV‐1 …

CCL3, a member of the CC-chemokine family, has been associated with macrophage
recruitment to heart tissue and parasite control in the acute infection of mouse with …

The comprehension of the molecular mechanisms leading to Trypanosoma cruzi-elicited
heart dysfunction might contribute to design novel therapeutic strategies aiming to …

Chronic cardiomyopathy is the main clinical manifestation of Chagas disease (CD), a
disease caused by Trypanosoma cruzi infection. A hallmark of chronic chagasic …

Chemokines are small chemoattractive proteins involved in many important physiological
and pathological processes such as leukocyte mobilisation, inflammation, cancer and HIV-1 …

One hundred years ago, Carlos Chagas discovered a new disease, the American
trypanosomiasis. Chagas and co-workers later characterised the disease's common …

Trypanosoma cruzi trypomastigotes invade a great variety of mammalian cells, with several
molecules being implicated in this complex event. Herein, the sequence GGIALAG present …

HIV infection is widespread throughout the world and is especially prevalent in sub-Saharan
Africa and Asia. Similarly, Plasmodium falciparum, the most common cause of severe …

ABSTRACT The Chagas' disease parasite Trypanosoma cruzi commonly infects humans
through skin abrasions or mucosa from reduviid bug excreta. Yet most studies on animal …