Glaucoma is one of the leading causes of vision impairment worldwide. In order to further
understand the molecular pathobiology of this disease and to develop better therapies …

Ischemia‐reperfusion (I/R) injury is one of the major causes of high morbidity, disability, and
mortality in the world. I/R injury remains a complicated and unresolved situation in clinical …

Acute ocular hypertension (AOH) is the most important characteristic of acute glaucoma,
which can lead to retinal ganglion cell (RGC) death and permanent vision loss. So far …

Retinal ischemia/reperfusion (I/R) injury is a common pathological process responsible for
cellular damage in glaucoma, diabetic retinopathy and hypertensive retinopathy. Metformin …

Background The aim of this study was to establish a complete retinal cell atlas of ischemia–
reperfusion injury by single-cell RNA sequencing, and to explore the underlying mechanism …

Complement dysregulation is a feature of many retinal diseases, yet mechanistic
understanding at the cellular level is limited. Given this knowledge gap about which retinal …

Retinal ischemia-reperfusion (I/R) is a pathophysiological process contributing to cellular
damage in multiple ocular conditions, including glaucoma, diabetic retinopathy, and retinal …

Oxidative stress is a hallmark of the pathophysiogenesis of retinal ischemia. The direct
delivery of antioxidant enzymes such as superoxide dismutase (SOD) into retinal cells …

Recent studies have shown that Connexin43 mimetic peptide (Cx43 MP) can prevent
secondary damage following retinal ischaemic and inflammatory disorders by blocking …

Retinal ischemia–reperfusion (RIR) injury caused by high intraocular pressure (IOP) is an
important risk factor contributing to retinal ganglion cell (RGC) death, eventually causing …