The functional complexity of the central nervous system (CNS) is unparalleled in living
organisms. Its nested cells, circuits and networks encode memories, move bodies and …

As antiretroviral therapy (ART) becomes increasingly affordable and accessible to women of
childbearing age across the globe, the number of children who are exposed to Human …

In vitro neuronal models have become an important tool to study healthy and diseased
neuronal circuits. The growing interest of neuroscientists to explore the dynamics of …

Three-dimensional (3D) in vitro cell and tissue culture models, particularly for the central
nervous system, allow for the exploration of mechanisms of organ development, cellular …

Neuronal cultures are one of the most important experimental models in modern
interdisciplinary neuroscience, allowing to investigate in a control environment the …

Microfluidics has played a vital role in developing novel methods to investigate biological
phenomena at the molecular and cellular level during the last two decades. Microscale …

A signature trait of neurotropic α-herpesviruses (α-HV) is their ability to establish stable non-
productive infections of peripheral neurons termed latency. This specialized gene …

To highlight the particular needs with respect to modeling the unique and complex
organization of the human brain structure, we reviewed the state-of-the-art in devising brain …

Part of the lacrimal functional unit, the cornea protects the ocular surface from numerous
environmental aggressions and xenobiotics. Toxicological evaluation of compounds …

Growing primary cells and tissue in long-term cultures, such as primary neural cell culture,
presents many challenges. A critical component of any environment that supports neural cell …