[HTML][HTML] AxonQuant: a microfluidic chamber culture-coupled algorithm that allows high-throughput quantification of axonal damage
Y Li, M Yang, Z Huang, X Chen, MT Maloney, L Zhu… - Neurosignals, 2014 - karger.com
Published methods for imaging and quantitatively analyzing morphological changes in
neuronal axons have serious limitations because of their small sample sizes, and their time …
neuronal axons have serious limitations because of their small sample sizes, and their time …
[HTML][HTML] Nanofabricating neural networks: strategies, advances, and challenges
R Luttge - Journal of Vacuum Science & Technology B, 2022 - pubs.aip.org
Nanofabrication can help us to emulate natural intelligence. Forward-engineering brain
gained enormous momentum but still falls short in human neurodegenerative disease …
gained enormous momentum but still falls short in human neurodegenerative disease …
Trusting the forces of our cell lines
Cells isolated from their native tissues and cultured in vitro face different selection pressures
than those cultured in vivo. These pressures induce a profound transformation that reshapes …
than those cultured in vivo. These pressures induce a profound transformation that reshapes …
Cultivation of purified primary purkinje cells from rat cerebella
J Tjaden, L Pieczora, F Wach, C Theiss… - Cellular and Molecular …, 2018 - Springer
Primary neurons are difficult to cultivate because they are often part of a complex tissue, and
synaptically connected to numerous other cell types. These circumstances often prevent us …
synaptically connected to numerous other cell types. These circumstances often prevent us …
Less Is More: Oligomer Extraction and Hydrothermal Annealing Increase PDMS Adhesion Forces for Materials Studies and for Biology-Focused Microfluidic …
LJ Millet, A Jain, MU Gillette - Micromachines, 2023 - mdpi.com
Cues in the micro-environment are key determinants in the emergence of complex cellular
morphologies and functions. Primary among these is the presence of neighboring cells that …
morphologies and functions. Primary among these is the presence of neighboring cells that …
Spontaneous Cell Cluster Formation in Human iPSC-Derived Neuronal Spheroid Networks Influences Network Activity
CJ Hörberg, UE Johansson, F Johansson, D O'carroll - eneuro, 2022 - eneuro.org
Three-dimensional neuronal culture systems such as spheroids, organoids, and
assembloids constitute a branch of neuronal tissue engineering that has improved our ability …
assembloids constitute a branch of neuronal tissue engineering that has improved our ability …
Optimized heterologous transfection of viable adult organotypic brain slices using an enhanced gene gun
J Arsenault, JA O'Brien - BMC Research Notes, 2013 - Springer
Background Organotypic brain slices (OTBS) are an excellent experimental compromise
between the facility of working with cell cultures and the biological relevance of using animal …
between the facility of working with cell cultures and the biological relevance of using animal …
Understanding, engineering, and modulating the growth of neural networks: An interdisciplinary approach
ABSTRACT A deeper understanding of the brain and its function remains one of the most
significant scientific challenges. It not only is required to find cures for a plethora of brain …
significant scientific challenges. It not only is required to find cures for a plethora of brain …
Macrofluidic recirculating model of skeletal metastasis
T Osawa, W Wang, J Dai, ET Keller - Scientific Reports, 2019 - nature.com
While microfluidic systems model aspects of metastasis, they are limited to artificially created
tissues of limited complexity. We set out to develop an in vitro model of tumor cell migration …
tissues of limited complexity. We set out to develop an in vitro model of tumor cell migration …
Influence of cortical synaptic input on striatal neuronal dendritic arborization and sensitivity to excitotoxicity in corticostriatal coculture
C Buren, G Tu, MP Parsons… - Journal of …, 2016 - journals.physiology.org
Corticostriatal cocultures are utilized to recapitulate the cortex-striatum connection in vitro as
a convenient model to investigate the development, function, and regulation of synapses …
a convenient model to investigate the development, function, and regulation of synapses …