Primary embryonic rat cortical neuronal culture and chronic rotenone treatment in microfluidic culture devices

VS Van Laar, B Arnold, SB Berman - Bio-protocol, 2019 - bio-protocol.org
In the study of neurodegenerative diseases, it is imperative to study the cellular and
molecular changes associated with pathogenesis in the relevant cell type, central nervous …

Microfluidics in neuroscience

P Gupta, N Balasubramaniam… - Microfluidics and Bio …, 2020 - taylorfrancis.com
Focused research in the field of neuroscience needs a microenvironment with
spatiotemporal fluidic control, which can be provided by microfluidic devices for guiding …

Regioselective biolistic targeting in organotypic brain slices using a modified gene gun

J Arsenault, A Nagy, JT Henderson… - JoVE (Journal of Visualized …, 2014 - jove.com
Transfection of DNA has been invaluable for biological sciences and with recent advances
to organotypic brain slice preparations, the effect of various heterologous genes could thus …

Additive manufacturing enables production of de novo cardiomyocytes by controlling embryoid body aggregation

R Das, JG Fernandez - Bioprinting, 2020 - Elsevier
Embryonic stem cells act as a valuable and promising resource in the field of regenerative
cell-based therapies and in studying various developmental models. These derived cells …

Microfluidic Devices for Analysis of Neuronal Development

MD Norsworthy, MU Gillette - Engineering Biomaterials for Neural …, 2022 - Springer
Investigation of brain structure and function can be conducted using various approaches
from whole organism behavior to the activity of individual molecules. Within this broad scope …

A microfluidic cell co-culture chip for the monitoring of interactions between macrophages and fibroblasts

P Li, F Cui, H Chen, Y Yang, G Li, H Mao, X Lyu - Biosensors, 2022 - mdpi.com
Macrophages and fibroblasts are two types of important cells in wound healing. The
development of novel platforms for studying the interrelationship between these two cells is …

Live Imaging Analysis of Axonal Regeneration in Human iPSC-Derived Motor Neurons Using a Microfluidic System

KL Marshall, MH Farah - Neuronal Morphogenesis: Methods and Protocols, 2024 - Springer
Axonal damage is a common feature of traumatic injury and neurodegenerative disease.
The capacity for axons to regenerate and to recover functionality after injury is a …

Comparison of two-and three-dimensional cancer models for assessing potential cancer therapeutics

B Xie, N Teusch, R Mrsny - Biomaterials for Cancer Therapeutics, 2020 - Elsevier
A plethora of molecules with the capacity to kill cancer cells have been identified through
intensive research efforts. These agents were typically identified using screens that involved …

Конструкционные особенности микрофлюидных устройств и области их применения

ЛВ Коваленко, МС Ощепков, АН Мыльникова… - Бутлеровские …, 2018 - elibrary.ru
Как известно, в последние десятилетия основные достижения науки связаны с
уменьшением размеров всевозможных лабораторных и диагностических устройств и …

Less is More: Oligomer extraction and hydrothermal annealing increase PDMS bonding forces for new microfluidics assembly and for biological studies

LJ Millet, A Jain, MU Gillette - bioRxiv, 2017 - biorxiv.org
Key determinants in the emergence of complex cellular morphologies and functions are
cues in the micro-environment. Primary among these is the presence of neighboring cells as …