A better understanding of mechanisms governing receptor insertion to the plasma
membrane (PM) requires an experimental approach with excellent spatial and temporal …

The limitations of current computation and artificial intelligence approaches have led to the
emergence of biological computation, which has been studied in the last years as an …

Huntington's disease (HD) is a genetic neurodegenerative disorder caused by expansion of
a CAG repeat in exon 1 of the HTT gene, encoding an elongated poly-glutamine repeat in …

The founding of the Journal of Experimental Zoology in 1904 was inspired by a widespread
turn toward experimental biology in the 19th century. The founding editors sought to promote …

Neuronal cultures are an excellent experimental tool to study the collective behaviour of
neuronal ensembles, providing information on the principles of synaptic functioning and …

The ability to maintain human brain explants in tissue culture was a critical step in the use of
these cells for the study of central nervous system disorders. Ross G. Harrison (1870–1959) …

Modern day ethics and laws call for more safety and use of fewer animals in biomedical
research. It became crucial to develop novel in vitro devices of higher relevance. Since the …

Understanding neuronal dynamics in normal and pathological conditions requires precise
electrophysiological measurements and detailed information about neuronal activity, as this …

A cell culturing platform for modeling myelination in vitro comprises first cell chambers
(102a, 102b) for containing somas of neuronal cells, a process chamber (103) connected to …

Neural interface research and development covers a wide spectrum of topics, spanning
basic neuroscience to design of implantable devices. In vitro studies have been an integral …