Small molecule metabolites: discovery of biomarkers and therapeutic targets

S Qiu, Y Cai, H Yao, C Lin, Y Xie, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

Blood oxylipin profiles as markers of oncological diseases

DV Chistyakov, LV Kovalenko, MY Donnikov… - Biochemistry …, 2023 - Springer
Oxylipins are signal lipid molecules formed from polyunsaturated fatty acids (PUFAs) in
several multienzymatic metabolic pathways, such as cyclooxygenase (COX), lipoxygenase …

Metabolomic biomarkers in liquid biopsy: accurate cancer diagnosis and prognosis monitoring

W Wang, S Zhen, Y Ping, L Wang, Y Zhang - Frontiers in Oncology, 2024 - frontiersin.org
Liquid biopsy, a novel detection method, has recently become an active research area in
clinical cancer owing to its unique advantages. Studies on circulating free DNA, circulating …

[HTML][HTML] Biomarkers of coordinate metabolic reprogramming and the construction of a co-expression network in colorectal cancer

L Lin, X Zeng, S Liang, Y Wang, X Dai… - Annals of Translational …, 2022 - ncbi.nlm.nih.gov
Background Globally, the incidence and mortality of colorectal cancer (CRC) rank amongst
the highest of all malignancies. Thus, research aimed at developing new screening …

Serum metabonomic study to explore the amelioration mechanisms of co‐fermented collagen peptide‐jackfruit juice on the immunosuppressed mice

T Ma, M Cheng, X Wen, K Zhu, X Zhang, C Zhao… - eFood, 2024 - Wiley Online Library
The main purpose of this study was to investigate the improvement effect and serum
metabolomic analysis of co‐fermented collagen peptide‐jackfruit juice (FPJ) against …

[HTML][HTML] Role of dietary nutrients and metabolism in colorectal cancer

J Ye, X Bao, J Wei, Y Zhang, Y Liu… - Asia Pacific Journal of …, 2024 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most common malignancies and the leading causes
of cancer related deaths worldwide. The development of CRC is driven by a combination of …

[HTML][HTML] 血清非靶向代谢组学联合靶向胆汁酸代谢组学筛查结直肠癌的潜在生物标志物

王旋成, 朱一帆, 周海琳, 黄宗声, 陈鸿炜… - Journal of Southern …, 2023 - ncbi.nlm.nih.gov
血清非靶向代谢组学联合靶向胆汁酸代谢组学筛查结直肠癌的潜在生物标志物- PMC Back to Top
Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …

Integrated analysis of serum untargeted metabolomics and targeted bile acid metabolomics for identification of diagnostic biomarkers for colorectal cancer

X Wang, Y Zhu, H Zhou, Z Huang, H Chen… - … Fang yi ke da xue xue …, 2023 - europepmc.org
Objective To identify potential diagnostic biomarkers of colorectal cancer (CRC) using serum
metabolomic technology for minimally invasive and efficient screening for CRC. Methods …

Blood oxylipin profiles as a marker of the pathogenesis of oncological diseases

DV Chistyakov, LV Kovalenko, MY Donnikov… - Biohimiâ, 2023 - journals.rcsi.science
Oxylipins are signal lipids derived from polyunsaturated fatty acids (PUFAs), which are
formed by polyenzymatic multi-acid pathways of danger (cyclooxygenase, lipoxygenase …

[PDF][PDF] АНАЛИЗ ПРОФИЛЯ ОКСИЛИПИНОВ В БИОЛОГИЧЕСКИХ ОБРАЗЦАХ КАК НОВЫЙ ПОДХОД К ИЗУЧЕНИЮ МЕХАНИЗМОВ ДЕЙСТВИЯ …

ДВ Чистяков - rudn.ru
Актуальность темы исследования. Одним из ключевых факторов патогенеза широкого
спектра заболеваний, включая онкологические и неврологические, является …