Green synthesis of nanoparticles and their biomedical applications: a review

N Shreyash, S Bajpai, MA Khan, Y Vijay… - ACS Applied Nano …, 2021 - ACS Publications
In the arena of material sciences, one of the burning topics for research has been
biogenically synthesizing nanoparticles (NPs) from plant derivatives and studying their …

Carboxylesterase inhibitors from clinically available medicines and their impact on drug metabolism

YQ Song, Q Jin, DD Wang, J Hou, LW Zou… - Chemico-Biological …, 2021 - Elsevier
Mammalian carboxylesterases (CES), the key members of the serine hydrolase superfamily,
hydrolyze a wide range of endogenous substances and xenobiotics bearing ester or amide …

Green supercapacitor: review and perspectives of sustainable template-free synthesis of metal and metal oxide nanoparticle

J Meena, SS Sivasubramaniam, E David… - RSC …, 2024 - pubs.rsc.org
Researchers are committed to thoroughly investigating the sustainable production of
supercapacitor electrode materials with enhanced properties. Supercapacitors are …

Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors

Y Yang, Y Xiong, G Zhu, M Sun, K Zou, Y Zhao… - Chemico-Biological …, 2023 - Elsevier
Abstract Human carboxylesterase 2A (hCES2A) is a key serine hydrolase responsible for
the metabolic clearance of large number of compounds bearing the ester-or amide-bond (s) …

[HTML][HTML] Discovery and Characterization of the Biflavones From Ginkgo biloba as Highly Specific and Potent Inhibitors Against Human Carboxylesterase 2

YQ Song, RJ He, D Pu, XQ Guan, JH Shi… - Frontiers in …, 2021 - frontiersin.org
Human carboxylesterase 2 (CES2), one of the most abundant hydrolases distributed in the
small intestine, has been validated as a key therapeutic target to ameliorate the intestinal …

[HTML][HTML] New trends in the practical use of isoquinoline alkaloids as potential drugs applicated in infectious and non-infectious diseases

T Tuzimski, A Petruczynik - Biomedicine & Pharmacotherapy, 2023 - Elsevier
In the last years, traditional natural products have been the center of attention for the
scientific community and exploration of their therapeutic abilities is proceeding permanently …

Discovery of hCES2A inhibitors from Glycyrrhiza inflata via combination of docking-based virtual screening and fluorescence-based inhibition assays

YQ Song, XQ Guan, ZM Weng, JL Liu, J Chen… - Food & function, 2021 - pubs.rsc.org
Human carboxylesterase 2 (hCES2A) is a key target to ameliorate the intestinal toxicity
triggered by irinotecan that causes severe diarrhea in 50%–80% of patients receiving this …

Tight-Binding Small-Molecule Carboxylesterase 2 Inhibitors Reduce Intracellular Irinotecan Activation

K Kailass, D Casalena, L Jenane… - Journal of medicinal …, 2024 - ACS Publications
As the primary enzyme responsible for the activatable conversion of Irinotecan (CPT-11) to
SN-38, carboxylesterase 2 (CES2) is a significant predictive biomarker toward CPT-11 …

Near-infrared fluorescent probe based on carboxylesterase 2 and viscosity cascade response for early diagnosis of thyroid cancer

W Luo, Q Diao, L Lv, T Li, P Ma, D Song - Sensors and Actuators B …, 2024 - Elsevier
Abstract Carboxylesterase 2 (CES2) plays a critical role in the metabolism of ester-and
amide-containing drugs and thus has an impact on drug efficacy and toxicity. This study …

Regulation of carboxylesterases and its impact on pharmacokinetics and pharmacodynamics: an up-to-date review

Y Liu, J Li, HJ Zhu - Expert Opinion on Drug Metabolism & …, 2024 - Taylor & Francis
ABSTRACT Introduction Carboxylesterase 1 (CES1) and carboxylesterase 2 (CES2) are
among the most abundant hydrolases in humans, catalyzing the metabolism of numerous …