New bysspectin A derivatives as potent inhibitors of human carboxylesterase 2A
W Li, Y Zhang, Y Wu, G Zhu, X Liu, Y Song, B Ma… - European Journal of …, 2023 - Elsevier
Abstract Human carboxylesterase 2A (hCES2A), the most abundant carboxylesterase in the
human gut, plays a crucial role in the metabolic clearance and activation of various ester …
human gut, plays a crucial role in the metabolic clearance and activation of various ester …
A UHPLC-QTOF-MS/MS method with a superimposed multiple product ion strategy and esterase inhibitor improved sensitivity for the determination of xylocarpin H in …
B Zhang, X Li, Y Liu, Z Tao, J Xiang, Y Wu… - … of Pharmaceutical and …, 2022 - Elsevier
Xylocarpin H is a natural limonoid that has the potential to be a viable therapeutic candidate
whether used alone or in combination with other medications. However, the …
whether used alone or in combination with other medications. However, the …
Preparation of a Highly Selective “Off-On” Rhodamine-Based Fluorescent Probe for the Specific Determination of Carboxylesterase 2 and Cell Imaging
J Song, J Yu, K Sun, Z Chen, X Xing, Y Yang… - Analytical …, 2023 - Taylor & Francis
Given the important role of carboxylesterase 2 (CES2) in the metabolism of various esters, it
is of significance to develop a tool to determine endogenous CES2 activity in a rapid and …
is of significance to develop a tool to determine endogenous CES2 activity in a rapid and …
Discovery of triterpenoids as potent dual inhibitors of pancreatic lipase and human carboxylesterase 1
J Zhang, QS Pan, XK Qian, XL Zhou… - Journal of Enzyme …, 2022 - Taylor & Francis
Pancreatic lipase (PL) is a well-known key target for the prevention and treatment of obesity.
Human carboxylesterase 1A (hCES1A) has become an important target for the treatment of …
Human carboxylesterase 1A (hCES1A) has become an important target for the treatment of …