Abstract CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats-
associated protein 9) is a potent technology for gene-editing. Owing to its high specificity …

The incidence and mortality of breast cancer (BC) have increased in recent years, and BC is
the main cause of cancer-related death in women worldwide. One of the most significant …

Cholangiocarcinoma (CCA) is a rare, aggressive disease with poor overall survival. In
advanced cases, surgery is often not possible or fails; in addition, there is a lack of effective …

Cancer is characterized by uncontrolled cell growth, disrupted regulatory pathways, and the
accumulation of genetic mutations. These mutations across different types of cancer lead to …

Cancer is one of the most leading causes of death and a major public health problem,
universally. According to accumulated data, annually, approximately 8.5 million people died …

Clustered regularly interspaced short palindromic repeats‐associated protein
(CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust …

The use of biomaterials in delivering CRISPR/Cas9 for gene therapy in infectious diseases
holds tremendous potential. This innovative approach combines the advantages of …

RNA interference (RNAi) is being extensively investigated as a potential therapeutic strategy
for cancer treatment. However, RNAi-based therapeutics have not yet been used to treat …

Cancer is a devastating condition characterised by the uncontrolled division of cells with
many forms remaining resistant to current treatment. A hallmark of cancer is the gradual …

The CRISPR-Cas system is a powerful tool for in vivo editing the genome of most organisms,
including man. During the years this technique has been applied in several fields, such as …