[HTML][HTML] The gut microbiota at the service of immunometabolism

C Michaudel, H Sokol - Cell metabolism, 2020 - cell.com
The gut microbiota is implicated in immune system functions. Regulation of the metabolic
processes occurring in immune cells is crucial for the maintenance of homeostasis and …

Management strategies to improve outcomes of patients with inflammatory bowel diseases

JF Colombel, N Narula, L Peyrin-Biroulet - Gastroenterology, 2017 - Elsevier
Strategies for management of inflammatory bowel diseases are shifting from simple control
of symptoms toward full control of these diseases (clinical and endoscopic remission), with …

Mitochondria and inflammatory bowel diseases: toward a stratified therapeutic intervention

G Ho, AL Theiss - Annual review of physiology, 2022 - annualreviews.org
Mitochondria serve numerous critical cellular functions, rapidly responding to extracellular
stimuli and cellular demands while dynamically communicating with other organelles …

ROS in gastrointestinal inflammation: rescue or sabotage?

G Aviello, UG Knaus - British journal of pharmacology, 2017 - Wiley Online Library
The intestine is composed of many distinct cell types that respond to commensal microbiota
or pathogens with immune tolerance and proinflammatory signals respectively. ROS …

[HTML][HTML] Mitochondrial dysfunction in inflammatory bowel disease

EA Novak, KP Mollen - Frontiers in cell and developmental biology, 2015 - frontiersin.org
Inflammatory Bowel Disease (IBD) represents a group of idiopathic disorders characterized
by chronic or recurring inflammation of the gastrointestinal tract. While the exact etiology of …

Diagnostics of inflammatory bowel disease

S Nikolaus, S Schreiber - Gastroenterology, 2007 - Elsevier
The diagnosis of inflammatory bowel disease (IBD) with its 2 main subforms, Crohn's
disease and ulcerative colitis, is based on clinical, endoscopic, radiologic, and histologic …

Inflammatory bowel disease: mechanisms, redox considerations, and therapeutic targets

F Biasi, G Leonarduzzi, PI Oteiza… - Antioxidants & redox …, 2013 - liebertpub.com
Oxidative stress is thought to play a key role in the development of intestinal damage in
inflammatory bowel disease (IBD), because of its primary involvement in intestinal cells' …

[HTML][HTML] Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes

C Moschandrea, V Kondylis, I Evangelakos, M Herholz… - Nature, 2024 - nature.com
Digested dietary fats are taken up by enterocytes where they are assembled into pre-
chylomicrons in the endoplasmic reticulum followed by transport to the Golgi for maturation …

[HTML][HTML] The role of microbiota-mitochondria crosstalk in pathogenesis and therapy of intestinal diseases

Y Zhang, J Zhang, L Duan - Pharmacological research, 2022 - Elsevier
The interaction between mitochondria and gut microbiota plays a critical role in intestinal
physiological homeostasis. In this kind of homeostasis, intestinal epithelial hypoxia helps …

Mechanism of deoxynivalenol mediated gastrointestinal toxicity: Insights from mitochondrial dysfunction

S Wang, K Wu, D Xue, C Zhang, SA Rajput… - Food and Chemical …, 2021 - Elsevier
Deoxynivalenol (DON) is a mycotoxin predominantly produced by Fusarium genus, and
widely contaminates cereals and associated products all over the world. The intestinal …