Conspectus Harnessing biocatalysts for novel abiological transformations is a longstanding
goal of synthetic chemistry. Combining the merits of biocatalysis and photocatalysis allows …

Natural products account for more than 50% of all small-molecule pharmaceutical agents
currently in clinical use. However, low availability often becomes problematic when a …

Exploiting nature's catalysts for non-natural transformations that are inaccessible to
chemocatalysis is highly desirable but challenging. On the one hand, the widespread …

Hydride transfers are key to a number of economically and environmentally important
reactions, including H2 evolution and NADH regeneration. The electrochemical generation …

Recent studies of multiple enzyme families collectively called ene-reductases (ERs) have
highlighted potential industrial applications of these biocatalysts in the production of fine and …

Photocatalytic regeneration of the high-cost co-factor NADH is a promising method to couple
photo-enzyme catalysis, however, the usage of homogeneous electron mediator ([Cp* Rh …

In the field of green chemistry, light–an attractive natural agent–has received particular
attention for driving biocatalytic reactions. Moreover, the implementation of light to drive …

Given the high costs and stoichiometric amounts of reduced nicotinamide adenine
dinucleotide (NADH) required by the many oxidoreductases used for organic synthesis and …

From Egyptian mummies to the Chanel n° 5 perfume, fatty aldehydes have long been used
and keep impacting our senses in a wide range of foods, beverages and perfumes. Natural …

Cofactors, such as nicotinamide adenine dinucleotide (NADH) or its phosphorylated
derivative (NADPH), are playing essential roles in redox enzymatic catalysis because of …