[HTML][HTML] Heartworm disease–Overview, intervention, and industry perspective
S Noack, J Harrington, DS Carithers… - International Journal for …, 2021 - Elsevier
Dirofilaria immitis, also known as heartworm, is a major parasitic threat for dogs and cats
around the world. Because of its impact on the health and welfare of companion animals …
around the world. Because of its impact on the health and welfare of companion animals …
Microfluidic systems for cancer diagnosis and applications
Microfluidic devices have led to novel biological advances through the improvement of micro
systems that can mimic and measure. Microsystems easily handle sub-microliter volumes …
systems that can mimic and measure. Microsystems easily handle sub-microliter volumes …
Caenorhabditis elegans as a model system for target identification and drug screening against neurodegenerative diseases
L Ma, Y Zhao, Y Chen, B Cheng, A Peng… - European Journal of …, 2018 - Elsevier
Over the past decades, Caenorhabditis elegans (C. elegans) has been widely used as a
model system because of its small size, transparent body, short generation time and lifespan …
model system because of its small size, transparent body, short generation time and lifespan …
The Role of Ca2+ Signaling in Aging and Neurodegeneration: Insights from Caenorhabditis elegans Models
J Alvarez, P Alvarez-Illera, P García-Casas, RI Fonteriz… - Cells, 2020 - mdpi.com
Ca2+ is a ubiquitous second messenger that plays an essential role in physiological
processes such as muscle contraction, neuronal secretion, and cell proliferation or …
processes such as muscle contraction, neuronal secretion, and cell proliferation or …
Cell-based drug screening on microfluidics
With the inherent merits of a low reagent consumption, the small amount of sample needed
and easy integration, a wide variety of microfluidic platforms (continuous-flow, droplet, digital …
and easy integration, a wide variety of microfluidic platforms (continuous-flow, droplet, digital …
High-throughput behavioral screen in C. elegans reveals Parkinson's disease drug candidates
We recently linked branched-chain amino acid transferase 1 (BCAT1) dysfunction with the
movement disorder Parkinson's disease (PD), and found that RNAi-mediated knockdown of …
movement disorder Parkinson's disease (PD), and found that RNAi-mediated knockdown of …
Microfluidic chambers using fluid walls for cell biology
C Soitu, A Feuerborn, AN Tan… - Proceedings of the …, 2018 - National Acad Sciences
Many proofs of concept have demonstrated the potential of microfluidics in cell biology.
However, the technology remains inaccessible to many biologists, as it often requires …
However, the technology remains inaccessible to many biologists, as it often requires …
Fluorescence-based sorting of Caenorhabditis elegans via acoustofluidics
Effectively isolating and categorizing large quantities of Caenorhabditis elegans (C.
elegans) based on different phenotypes is important for most worm research, especially …
elegans) based on different phenotypes is important for most worm research, especially …
Drug discovery technologies: Caenorhabditis elegans as a model for anthelmintic therapeutics
D Sepúlveda‐Crespo, RM Reguera… - Medicinal research …, 2020 - Wiley Online Library
Helminthiasis is one of the gravest problems worldwide. There is a growing concern on less
available anthelmintics and the emergence of resistance creating a major threat to human …
available anthelmintics and the emergence of resistance creating a major threat to human …
Studying Parkinson's disease using Caenorhabditis elegans models in microfluidic devices
Parkinson's disease (PD) is a progressive neurological disorder associated with the loss of
dopaminergic neurons (DNs) in the substantia nigra and the widespread accumulation of α …
dopaminergic neurons (DNs) in the substantia nigra and the widespread accumulation of α …