[HTML][HTML] Mucosal vaccines—fortifying the frontiers

EC Lavelle, RW Ward - Nature Reviews Immunology, 2022 - nature.com
Mucosal vaccines offer the potential to trigger robust protective immune responses at the
predominant sites of pathogen infection. In principle, the induction of adaptive immunity at …

[HTML][HTML] Mucosal immune responses to infection and vaccination in the respiratory tract

RC Mettelman, EK Allen, PG Thomas - Immunity, 2022 - cell.com
The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …

[HTML][HTML] The burden of bacterial antimicrobial resistance in the WHO European region in 2019: a cross-country systematic analysis

T Mestrovic, GR Aguilar, LR Swetschinski… - The Lancet Public …, 2022 - thelancet.com
Background Antimicrobial resistance (AMR) represents one of the most crucial threats to
public health and modern health care. Previous studies have identified challenges with …

[HTML][HTML] Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

CJL Murray, KS Ikuta, F Sharara, L Swetschinski… - The lancet, 2022 - thelancet.com
Background Antimicrobial resistance (AMR) poses a major threat to human health around
the world. Previous publications have estimated the effect of AMR on incidence, deaths …

[HTML][HTML] Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019

KS Ikuta, LR Swetschinski, GR Aguilar, F Sharara… - The Lancet, 2022 - thelancet.com
Background Reducing the burden of death due to infection is an urgent global public health
priority. Previous studies have estimated the number of deaths associated with drug …

[HTML][HTML] Changes in the incidence of invasive disease due to Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis during the COVID-19 …

AB Brueggemann, MJJ van Rensburg… - The Lancet Digital …, 2021 - thelancet.com
Summary Background Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria
meningitidis, which are typically transmitted via respiratory droplets, are leading causes of …

RSV prefusion f protein–based maternal vaccine—preterm birth and other outcomes

I Dieussaert, J Hyung Kim, S Luik, C Seidl… - … England Journal of …, 2024 - Mass Medical Soc
Background Vaccination against respiratory syncytial virus (RSV) during pregnancy may
protect infants from RSV disease. Efficacy and safety data on a candidate RSV prefusion F …

[HTML][HTML] Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019

HH Kyu, A Vongpradith, SB Sirota… - The Lancet Infectious …, 2022 - thelancet.com
Background The global burden of lower respiratory infections (LRIs) and corresponding risk
factors in children older than 5 years and adults has not been studied as comprehensively …

[HTML][HTML] Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality …

KR Paulson, AM Kamath, T Alam, K Bienhoff… - The Lancet, 2021 - thelancet.com
Summary Background Sustainable Development Goal 3.2 has targeted elimination of
preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths …

[HTML][HTML] The burden of bacterial antimicrobial resistance in the WHO African region in 2019: a cross-country systematic analysis

B Sartorius, AP Gray, ND Weaver, GR Aguilar… - The Lancet Global …, 2024 - thelancet.com
Background A critical and persistent challenge to global health and modern health care is
the threat of antimicrobial resistance (AMR). Previous studies have reported a …