In this work, we develop mathematical models of the immune response to respiratory viral
infection, taking into account some particular properties of the SARS-CoV infections …

Sepsis is a form of life-threatening organ dysfunction caused by dysregulated host
responses to an infection that can be partly attributed to immune dysfunction. Although …

Immunosuppression is one hallmark of sepsis, decreasing the host response to the primary
septic pathogens and/or secondary nosocomial infections. CD4 T cells and B cells are …

The main methods for the evaluation of natural killer (NK, CD16+ CD56+) cells, interleukins
and related subsets of lymphocytes are briefly described. Moderate endurance exercise …

The neisserial porins are the major protein components of the outer membrane of the
pathogenic Neisseria (N. meningitidis and N. gonorrhoeae). They have been shown to be …

Publisher Summary This chapter focuses on the biochemistry of B lymphocyte activation. It
describes the current state of knowledge about the nature of B cell antigen receptors, their …

Although calpain is ubiquitously present in human tissues and is thought to play a role in
demyelination, its activity is very low in resting normal lymphocytes. To determine the nature …

A major feature of the immature immune system in the newborn is its inability to produce
significant levels of immunoglobulins other than IgM in response to antigens. It has recently …

This invention provides a monoclonal antibody which specifically recognizes and forms a
complex with a protein located on the surface of activated T cells and thereby inhibits T cell …

Stimulation of CD86 (formerly known as B7-2) and/or the β 2-adrenergic receptor on a CD40
ligand/interleukin-4-activated B cell increased the rate of mature IgG 1 transcription. To …