Method for suppressing xenograft rejection

TWT Wiedmann, J Wang - US Patent 5,759,550, 1998 - Google Patents
This application is a continuation-in-part of Ser. No. 08/307,948 filed Sep. 15, 1994, now
abandoned, which is a continuation-in-part of Ser. No. 08/222,853 filed Apr. 5, 1994, now …

Modern concepts in immune recognition and lymphocyte activation: relevance for the development of useful vaccines

RN Germain - International journal of technology assessment in …, 1994 - cambridge.org
Adaptive immunity requires both specific recognition of an antigen and its translation into
appropriate lymphocyte responses. This paper reviews the striking differences in B-and T …

B cells do not present antigen covalently linked to microspheres.

A Galelli, B Charlot, E Deriaud, C Leclerc - Immunology, 1993 - ncbi.nlm.nih.gov
B cells have been shown to present antigen to T cells very efficiently through their capacity
to capture antigens by their membrane immunoglobulin. This direct cognate interaction of T …

T cells, cytokines, IgE and allergic inflammation

M Ricci - International archives of allergy and immunology, 1992 - karger.com
On the basis of results obtained in our and in other labs it is now possible to affirm that B
cells require different signals to be induced to IgE production. The first signal is delivered by …

3 Normal B lymphocyte differentiation

PD Burrows, JF Kearney, HW Schroeder Jr… - Baillière's clinical …, 1993 - Elsevier
Normal differentiation of B lineage cells has been the subject of intensive investigation over
the past three decades. Current models of this process in humans are melded from the …

Method for inhibiting inflammation with an antibody that binds the 5C8 protein

S Lederman, L Chess, MJ Yellin - US Patent 7,070,777, 2006 - Google Patents
US7070777B1 - Method for inhibiting inflammation with an antibody that binds the 5C8 protein
- Google Patents US7070777B1 - Method for inhibiting inflammation with an antibody that …

Intersite helper function of T cells specific for a protein epitope that is not recognized by antibodies

JS Rosenberg, MZ Atassi - Immunological investigations, 1997 - Taylor & Francis
Humoral responses to a protein require TB cell communication for B cell activation by T
cells. Previous studies from this laboratory have mapped the T and B cell recognition sites …

Methods to inhibit humoral immune responses, immunoglobulin production and B cell activation with 5c8-specific antibodies

S Lederman, L Chess, MJ Yellin - US Patent 5,993,816, 1999 - Google Patents
Dunham LLP 57 ABSTRACT This invention provides an isolated nucleic acid molecule
encoding a protein from the Surface of activated T cells, wherein the protein is necessary for …

Regulation of murine germinal centre cell proliferation in vivo: A stathmokinetic study examining the effect of differently timed doses of cyclosporin A

JR Goodlad, JC Macartney - The Journal of Pathology, 1995 - Wiley Online Library
Although studies have identified factors which affect germinal centre cell proliferation in vitro,
their relative contributions in vivo remain largely undetermined. In this study, the proliferative …

B cell responses to a peptide epitope. VI. The kinetics of antigen recognition modulates B cell-mediated recruitment of T helper subsets

L Vijayakrishnan, V Manivel, KVS Rao - The Journal of Immunology, 1998 - journals.aai.org
The ability of Ag-primed B cells to recruit distinct Th subsets was examined using two
analogous synthetic peptides, G41CT3 and G28CT3, as model Ags. With sequence …