Mononuclear cells from peripheral blood and bone marrow from patients with chronic
lymphocytic leukemia (CLL) were cultured with interleukin-4 (IL-4) alone or with IL-4 and …

Although our ability to care for major burns has improved over the last two decades, mortality
due to septic complications still remains a major threat to the survival of severely injured …

Publisher Summary This chapter focuses on several interrelated models that highlight the
importance of secondary lymphoid tissue function and cellular interactions during the …

The functional properties of two CD4+ CD8− CD16−, five CD4− CD8+ CD16− and three
CD4− CD8− CD16+ human T cell clones were compared. All CD4− T cell clones displayed …

This laboratory had previously mapped the regions of T and B cell recognition on sperm
whale myoglobin (Mb). Mb has five regions (E1-E5) that are recognized by both T cells and …

The ligand-receptor binding requirements for achieving full B cell activation through the
membrane immunoglobulin mIg signaling pathway are relatively demanding, and mIg …

Here we examined T cell responses to two analogs of a chimeric peptide encoding a known
B and a known T cell epitope. In one of the analogs, the B cell epitope existed in a random …

The potential for surface immunoglobulin-binding ligands to modify B-cell differentiation
responses induced by activated T cells has been investigated. Activated T cells in human …

It is a common practice in semi nomadic sheep farming to expose sheep to different degrees
of water deprivation, which leads to stress followed by different disease outbreaks. In this …

Publisher Summary The goal of the immune system is to establish and maintain separation
of self and nonself. Invasion of otherwise sterile tissues by nonself in the form of …